www.unimi.it bioscienze.bio Dipartimento Bioscienze

FotoGabriella Leccese
Email: gabriella.leccese@unimi.it
Cicle: XXXV A.Y. 2019 - 2020
Supervisor: Moira Paroni
Titol: Unveiling the AIEC-antigens and gut-microbiota species involved in modulation of pathogenic Th1/17 cells differentiation and activation in Crohn’s disease  … read more

PhD Courses:
Starting Date Ending Date Title Place
03/02/2020 07/02/2020 Molecular and Cellular Biology: Methods and Communication of Results Università degli studi di Milano
23/06/2020 30/06/2020 Introduction to transcriptomic data analysis Università degli studi di Milano
21/09/2020 21/09/2020 Virology: new advances in basic and applied research Università degli studi di Milano
13/01/2021 27/01/2021 Biostatistic for molecular and cellular biology MS Teams
04/05/2021 11/05/2021 Scientific visualization of molecular processes in the cellular environment Milano
24/05/2021 25/05/2021 Flow cytometry in biomedical research Milano

Conferences / Workshops:
Starting Date Ending Date Title Place
18/09/2019 21/09/2019 47° congresso nazionale della società italiana microbiologia Università Pontificia "Angelicum" San Tommaso d'Aquino, Roma
26/05/2021 28/05/2021 Novel Concepts in Innate Immunity Online

PUBLICATIONS

 Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive Escherichia coli (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease
Gabriella Leccese, Alessia Bibi, Stefano Mazza, Federica Facciotti, Flavio Caprioli, Paolo Landini, Moira Paroni
Cells

 IBDs and the pediatric age: Their peculiarities and the involvement of the microbiota
Lucia Cococcioni, Simona Panelli, Ilaria Varotto-Boccazzi, Domenico Di Carlo, Dario Pistone, Gabriella Leccese, Gian Vincenzo Zuccotti, Francesco Comandatore
Digestive and Liver disease

Curriculum vitae: >>>




Immagine linee di ricerca
Expression of CD40L and IL-17 of intestinal Th1/17 cell lines from CD patients in response to autologous monocytes in the presence of bacterial antigens (heat-inactivated AIEC). A particular subset of Th1/17 cells, called Th1/17* cells, specifically recognize AIEC, coproducing high levels of pathogenic cytokines (IFN-γ, IL-17, GM-CSF).



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