Gabriella Leccese
Email: gabriella.leccese@unimi.it
Cicle: XXXV A.Y. 2019 - 2020
Supervisor: Moira Paroni
Title: Unveiling the AIEC-antigens and gut-microbiota species involved in modulation of pathogenic Th1/17 cells differentiation and activation in Crohn’s disease  … read more

External links: ORCID


Curriculum vitae: >>>


PhD Courses:

Starting Date	Ending Date	Title	Place
03/02/2020	07/02/2020	Molecular and Cellular Biology: Methods and Communication of Results	Università degli studi di Milano
23/06/2020	30/06/2020	Introduction to transcriptomic data analysis	Università degli studi di Milano
21/09/2020	21/09/2020	Virology: new advances in basic and applied research	Università degli studi di Milano
13/01/2021	27/01/2021	Biostatistic for molecular and cellular biology	MS Teams
04/05/2021	11/05/2021	Scientific visualization of molecular processes in the cellular environment	Milano
24/05/2021	25/05/2021	Flow cytometry in biomedical research	Milano

Conferences / Workshops:

Starting Date	Ending Date	Title	Place
18/09/2019	21/09/2019	47° congresso nazionale della società italiana microbiologia	Università Pontificia "Angelicum" San Tommaso d'Aquino, Roma
26/05/2021	28/05/2021	Novel Concepts in Innate Immunity	Online
04/04/2022	08/04/2022	Pathogen Immunity and Signaling	Saint Malo, France
28/05/2022	01/06/2022	Lymphocyte antigen receptor signaling - EMBO	Castelnuovo Berardenga
23/06/2022	25/06/2022	Cortona Procarioti - SIMGBM	Cortona, Italy

Publications:

 Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive Escherichia coli (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease
Gabriella Leccese, Alessia Bibi, Stefano Mazza, Federica Facciotti, Flavio Caprioli, Paolo Landini, Moira Paroni
Cells

 IBDs and the pediatric age: Their peculiarities and the involvement of the microbiota
Lucia Cococcioni, Simona Panelli, Ilaria Varotto-Boccazzi, Domenico Di Carlo, Dario Pistone, Gabriella Leccese, Gian Vincenzo Zuccotti, Francesco Comandatore
Digestive and Liver disease

 Lack of Direct Correlation between Biofilm Formation and Antimicrobial Resistance in Clinical Staphylococcus epidermidis Isolates from an Italian Hospital
Carcione D, Leccese G, Conte G, Rossi E, Intra J, Bonomi A, Sabella S, Moreo M, Landini P, Brilli M, Paroni M.
Microorganisms

 Inactivation of the Pyrimidine Biosynthesis pyrD Gene Negatively Affects Biofilm Formation and Virulence Determinants in the Crohn's Disease-Associated Adherent Invasive Escherichia coli LF82 Strain
Rossi E, Leccese G, Baldelli V, Bibi A, Scalone E, Camilloni C, Paroni M, Landini P.
Microorganisms.

Expression of CD40L and IL-17 of intestinal Th1/17 cell lines from CD patients in response to autologous monocytes in the presence of bacterial antigens (heat-inactivated AIEC). A particular subset of Th1/17 cells, called Th1/17* cells, specifically recognize AIEC, coproducing high levels of pathogenic cytokines (IFN-γ, IL-17, GM-CSF).