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A high affinity switch for cAMP in the HCN pacemaker channels DOI PubMedA. Porro, A. Saponaro, R. Castelli, B. Introini, A.H. Alkotob, G. Ranjbari, U. Enke, J. Kusch, K. Benndorf, B. Santoro, D. Difrancesco, G. Thiel, A. Moroni
Nature Communications
Mitochondria-derived reactive oxygen species are the likely primary trigger of mitochondrial retrograde signaling in Arabidopsis DOI PubMed
Kasim Khan, Huy Cuong Tran, Berivan Mansuroglu, Pinar Önsell, Stefano Buratti, Markus Schwarzländer, Alex Costa, Allan G Rasmusson, Olivier Van Aken
Current Biology
ALS' Perfect Storm: C9orf72-Associated Toxic Dipeptide Repeats as Potential Multipotent Disruptors of Protein Homeostasis DOI PubMed
P.H.Smeele, G. Cesare, T. Vaccari
Cells
The ALOG domain defines a family of plant-specific transcription factors acting during Arabidopsis flower development DOI PubMed
Philippe Rieu, Veronica Maria Beretta, Francesca Caselli, Emmanuel Thévénon, Jérémy Lucas, Mahmoud Rizk, Emanuela Franchini, Elisabetta Caporali, Chiara Paleni, Max H. Nanao, Martin M. Kater, Renaud Dumas, Chloe Zubieta, François Parcy, Veronica Gregis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Calcium-Driven In Silico Inactivation of a Human Olfactory Receptor DOI PubMed
Pirona L., Ballabio F., Alfonso-Prieto M., Capelli R.
Journal of Chemical Information and Modeling
Development of pollinated and unpollinated ovules in Ginkgo biloba: unravelling pollen's role in ovule tissue maturation DOI PubMed
Antonella Muto, Emanuela Talarico, Greta D'Apice, Maurizio Di Marzo, Silvia Moschin, Sebastiano Nigris, Nicola Babolin, Eleonora Greco, Fabrizio Araniti, Adriana Chiappetta, Lucia Colombo, Barbara Baldan, Leonardo Bruno
Journal of Experimental Botany
Serum antibody fingerprinting of SARS-CoV-2 variants in infected and vaccinated subjects by label-free microarray biosensor DOI PubMed
Thomas Carzaniga, Luca Casiraghi, Giovanni Nava, Giuliano Zanchetta, Tommaso Inzani, Marcella Chiari, Valentina Bollati, Sara Epis, Claudio Bandi, Alessia Lai, Gianguglielmo Zehender, Tommaso Bellini, Marco Buscaglia
Frontiers in Immunology
Site-directed mutagenesis reveals the interplay between stability, structure and enzymatic activity in RidA from Capra hircus DOI PubMed
Giulia Rizzi, Stefania Digiovanni, Genny Degani, Alberto Barbiroli, Flavio Di Pisa, Laura Popolo, Cristina Visentin, Maria Antonietta Vanoni, Stefano Ricagno
Protein Science
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A. Saponaro, J. H Krumbach, A. Chaves-Sanjuan, A. Sadat Sharifzadeh, A. Porro, R. Castelli, K. Hamacher, M. Bolognesi, D. DiFrancesco, O. B Clarke, G. Thiel, A. Moroni
PNAS
AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn's disease is suppressed by rfaP and ybaT deletion DOI PubMed
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Gut Microbes
Comparing GBA1‐Parkinson's disease and idiopathic Parkinson's disease: α‐Synuclein oligomers and synaptic density as biomarkers in the skin biopsy DOI PubMed
Samanta Mazzetti, Elena Contaldi, Milo Jarno Basellini, Claudia Novello, Alessandra Maria Calogero, Letizia Straniero, Federica Garrì, Valentina Ferri, Daniela Calandrella, Francesca Del Sorbo, Rosanna Asselta, Emanuele Cereda, Graziella Cappelletti, Ioannis Ugo Isaias, Gianni Pezzoli
Brain Pathology
Noninvasive In Planta Live Measurements of H2O2 and Glutathione Redox Potential with Fluorescent roGFPs-Based Sensors DOI PubMed
Stefano Buratti, Matteo Grenzi, Giorgia Tortora, Sara Paola Nastasi, Elisa Dell'Aglio, Andrea Bassi, Alex Costa
Methods in Molecular Biology
Nicotinic Acid Derivatives As Novel Noncompetitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment DOI PubMed
Citarella A., Cavinato M., Rosini E., Shehi H., Ballabio F., Camilloni C., Fasano V., Silvani A., Passarella D., Pollegioni L., Nardini M.
ACS Medicinal Chemistry Letters
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Silvia Moschin, Sebastiano Nigris, Elisabetta Ofer, Nicola Babolin, Adriana Chiappetta, Leonardo Bruno, Barbara Baldan
Planta - Springer
A missense mutation in the barley Xan-h gene encoding the Mg-chelatase subunit I leads to a viable pale green line with reduced daily transpiration rate DOI PubMed
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Plant Cell Reports
Nicotinic Acid Derivatives As Novel Non-competitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment DOI PubMed
Andrea Citarella, Miriam Cavinato, Elena Rosini, Haidi Shehi, Federico Ballabio, Carlo Camilloni, Valerio Fasano, Alessandra Silvani, Daniele Passarella, Loredano Pollegioni, Marco Nardini
ACS Medicinal Chemistry Letters
2023
Targeting the LPS export pathway for the development of novel therapeutics DOI PubMedSperandeo P, Martorana AM, Zaccaria M, Polissi A.
Biochim Biophys Acta Mol Cell Res.
Asexual reproduction through seeds: the complex case of diplosporous apomixis DOI PubMed
Letizia Cornaro, Camilla Banfi, Mara Cucinotta, Lucia Colombo, Peter J van Dijk
Journal of Experimental Botany
Two florigens and a florigen-like protein form a triple regulatory module at the shoot apical meristem to promote reproductive transitions in rice DOI PubMed
Francesca Giaume, Giulia Ave Bono, Damiano Martignago, Yiling Miao, Giulio Vicentini, Taiyo Toriba, Rui Wang, Dali Kong, Martina Cerise, Daniele Chirivì, Marco Biancucci, Bahman Khahani, Piero Morandini, Wladimir Tameling, Michela Martinotti, Daniela Goretti, George Coupland, Martin Kater, Vittoria Brambilla, Daisuke Miki, Junko Kyozuka & Fabio Fornara
Nature Plants
A missing piece in the control of rice flowering and inflorescence determinacy DOI PubMed
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Nature Plants
Human PNPase causes RNA stabilization and accumulation of R-loops in the Escherichia coli model system DOI PubMed
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Scientific Reports
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Science of The Total Environment
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Cell Death & Disease
Accurate and Efficient SAXS/SANS Implementation Including Solvation Layer Effects Suitable for Molecular Simulations DOI PubMed
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Journal of Chemical Theory and Computation
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 DOI PubMed
Bianca Cesaro, Alessia Iaiza, Fabio Piscopo, Marco Tarullo, Eleonora Cesari, Dante Rotili, Antonello Mai, Alberto Diana, Michela Londero, Luca Del Giacco, Riccardo Masetti, Alba Di Leone, Chiara Naro, Silvia Masciarelli, Giulia Fontemaggi, Claudio Sette, Francesco Fazi, Alessandro Fatica
Cancer Communications
Long-distance turgor pressure changes induce local activation of plant glutamate receptor-like channels DOI PubMed
Matteo Grenzi, Stefano Buratti, Ambra Selene Parmagnani, Ilaria Abdel Aziz, Iwona Bernacka-Wojcik, Francesca Resentini, Jan Šimura, Fabrizio Gandolfo Doccula, Andrea Alfieri, Laura Luoni, Karin Ljung, Maria Cristina Bonza, Eleni Stavrinidou, Alex Costa
Current Biology
Plant Ca2+-ATPases: From biochemistry to signalling DOI PubMed
Alex Costa, Francesca Resentini, Stefano Buratti, Maria Cristina Bonza
Biochimica Biophysica Acta. Molecular Cell Research
AMEBaS: Automatic Midline Extraction and Background Subtraction of Ratiometric Fluorescence Time-Lapses of Polarized Single Cells DOI PubMed
Rafael Badain, Daniel S C Damineli, Maria Teresa Portes, José Feijó, Stefano Buratti, Giorgia Tortora, Hugo Neves de Oliveira, Roberto M Cesar Jr
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Materials Today Bio
Bone marrow vasculature advanced in vitro models for cancer and cardiovascular research DOI PubMed
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Frontiers in Cardiovascular Medicine
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device DOI PubMed
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APL Bioengineering
Multi-eGO: Model Improvements toward the Study of Complex Self-Assembly Processes DOI PubMed
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Journal of Chemical Theory and Computation
2022
Activity and Function in Human Cells of the Evolutionary Conserved Exonuclease Polynucleotide Phosphorylase DOI PubMedFalchi FA, Pizzoccheri R, Briani F.
International Journal of Molecular Sciences
L- to D-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics DOI PubMed
Ballabio F., Broggini L., Paissoni C., Han X., Peqini K., Sala B.M., Sun R., Sandalova T., Barbiroli A., Achour A., Pellegrino S., Ricagno S., Camilloni C.
ACS Omega
Inactivation of the Pyrimidine Biosynthesis pyrD Gene Negatively Affects Biofilm Formation and Virulence Determinants in the Crohn’s Disease-Associated Adherent Invasive Escherichia coli LF82 Strain DOI PubMed
Rossi Elio, Gabriella Leccese, Valerio Baldelli, Alessia Bibi, Emanuele Scalone, Carlo Camilloni, Moira Paroni, and Paolo Landini
Microorganisms
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PNAS
Cell wall modifications by α-XYLOSIDASE1 are required for control of seed and fruit size in Arabidopsis DOI PubMed
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Journal of Experimental Botany
Synthesis and Characterization of Curcumin-Loaded Nanoparticles of Poly(Glycerol Sebacate): A Novel Highly Stable Anticancer System DOI PubMed
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Molecules
Pathogen Adaptation to American (Rpv3-1) and Eurasian (Rpv29) Grapevine Loci Conferring Resistance to Downy Mildew DOI PubMed
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Plants
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Emanuele Scalone, Luca Broggini, Cristina Visentin, Davide Erba, Fran Bačić Toplek, Kaliroi Peqini, Sara Pellegrino, Stefano Ricagno, Cristina Paissoni, Carlo Camilloni
Proceedings of the National Academy of Sciences
The Genetic Control of SEEDSTICK and LEUNIG-HOMOLOG in Seed and Fruit Development: New Insights into Cell Wall Control DOI PubMed
Maurizio Di Marzo, Nicola Babolin, Vívian Ebeling Viana, Antonio Costa de Oliveira, Bruno Gugi, Elisabetta Caporali, Humberto Herrera-Ubaldo, Eduardo Martínez-Estrada, Azeddine Driouich, Stefan de Folter, Lucia Colombo and Ignacio Ezquer
Plants
Apis mellifera RidA, a novel member of the canonical YigF/YER057c/UK114 imine deiminase superfamily of enzymes pre-empting metabolic damage DOI PubMed
Cristina Visentin, Giulia Rizzi, Genny Degani, Stefania Digiovanni, Giovanni Robecchi, Alberto Barbiroli, Laura Popolo, Maria Antonietta Vanoni, Stefano Ricagno
Biochemical and Biophysical Research Communications
Lack of Direct Correlation between Biofilm Formation and Antimicrobial Resistance in Clinical Staphylococcus epidermidis Isolates from an Italian Hospital DOI PubMed
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Microorganisms
Inactivation of the Pyrimidine Biosynthesis pyrD Gene Negatively Affects Biofilm Formation and Virulence Determinants in the Crohn's Disease-Associated Adherent Invasive Escherichia coli LF82 Strain DOI PubMed
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Microorganisms.
Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery DOI PubMed
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Molecular Therapy
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila DOI PubMed
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Cell Death and Disease
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Journal of Tissue Engineering
Using integrated meta-omics to appreciate the role of the gut microbiota in epilepsy DOI PubMed
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Neurobiology of Disease
2021
Generation of β cells from iPSC of a MODY8 patient with a novel mutation in the carboxyl ester lipase (CEL) gene DOI PubMedS Pellegrini, G B Pipitone, A Cospito, F Manenti, G Poggi, M T Lombardo, R Nano, G Martino, M Ferrari, P Carrera, V Sordi, L Piemonti
The Journal of Clinical Endocrinology & Metabolism
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Plant Cell
NF-Y Subunits Overexpression in HNSCC DOI PubMed
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Cancer
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Molecular Plant
Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos DOI PubMed
Anna Ghilardi, Alberto Diana, Renato Bacchetta, Nadia Santo, Miriam Ascagni, Laura Prosperi, and Luca Del Giacco1
International Journal of Molecular Sciences
Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation DOI PubMed
Roberto Quadri, Sarah Sertic, Anna Ghilardi, Diego Rondelli, Guido Roberto Gallo, Luca Del Giaccio, Marco Muzi-Falconi
International Journal of Molecular Sciences
The transcription factor NF-Y participates to stem cell fate decision and regeneration in adult skeletal muscle DOI PubMed
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Nature Communications
From single cells to flowers – Biological complexity driving plant reproductive development DOI PubMed
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Preprints
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Journal of Experimental & Clinical Cancer Research
Comparative Analysis of Genotyping by Sequencing and Whole-Genome Sequencing Methods in Diversity Studies of Olea europaea L DOI PubMed
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Plants
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Scientific Reports
VID22 counteracts G-quadruplex-induced genome instability DOI PubMed
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Nucleic Acids Research
NF-Y subunits overexpression in gastric adenocarcinomas (STAD) DOI PubMed
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Scientific Reports
Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles DOI PubMed
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European Heart Journal, Supplements
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bmc-bioinformatics
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”Ascan: a novel method for the study of inter-individual allele specific expression DOI PubMed
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Targeted knockout of the gene OsHOL1 removes methyl iodide emissions from rice plants DOI PubMed
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Scientific Reports
Anthocyanins: From Mechanisms of Regulation in Plants to Health Benefits in Foods DOI PubMed
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Frontiers in Plant Science
Multi- and Transgenerational Outcomes of an Exposure to a Mixture of Endocrine-Disrupting Chemicals (EDCs) on Puberty and Maternal Behavior in the Female Rat DOI PubMed
David López-Rodríguez, Carlos Francisco Aylwin, Virginia Delli, Elena Sevrin, Marzia Campanile, Marion Martin, Delphine Franssen, Arlette Gérard, Silvia Blacher, Ezio Tirelli, Agnès Noël, Alejandro Lomniczi, Anne-Simone Parent
Environmental Health Perspectives
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BPC Transcription Factors and a Polycomb Group Protein Confine the Expression of the Ovule Identity Gene SEEDSTICK in Arabidopsis DOI PubMedPetrella R., Caselli F., Roig-Villanova I., Vignati V., Chiara M., Ezquer I., Tadini L., Kater M. M., Gregis V.
The Plant Journal
Efficacy of Cholesterol Nose-to-Brain Delivery for Brain Targeting in Huntington's Disease DOI PubMed
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ACS Chemical Neuroscience
NF-YA Overexpression in Lung Cancer: LUAD DOI PubMed
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Integrating Peak Colocalization and Motif Enrichment Analysis for the Discovery of Genome-Wide Regulatory Modules and Transcription Factor Recruitment Rules DOI PubMed
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Frontiers in genetics
Barley’s Second Spring as a Model Organism for Chloroplast DOI PubMed
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Plants
Rad9/53BP1 promotes DNA repair via crossover recombination by limiting the Sgs1 and Mph1 helicases DOI PubMed
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NATURE COMMUNICATION
Expression pattern of the small muscle protein, X-linked (smpx) gene during zebrafish embryonic and larval developmental stages DOI PubMed
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Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors DOI PubMed
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Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive Escherichia coli (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease DOI PubMed
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PLOS Genetics
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Scientific Reports
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Cells
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International Journal of Molecular Sciences
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Neurobiology of Disease
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Nature Communications
NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC) DOI PubMed
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Int. J. Mol. Sc
IBDs and the pediatric age: Their peculiarities and the involvement of the microbiota DOI PubMed
Lucia Cococcioni, Simona Panelli, Ilaria Varotto-Boccazzi, Domenico Di Carlo, Dario Pistone, Gabriella Leccese, Gian Vincenzo Zuccotti, Francesco Comandatore
Digestive and Liver disease
On the NF-Y regulome as in ENCODE (2019). DOI PubMed
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PLoS Computational Biology
The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action DOI PubMed
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Front Pharmacol
Tau and DNA Damage in Neurodegeneration DOI PubMed
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Brain Sciences
OsFD4 promotes the rice floral transition via florigen activation complex formation in the shoot apical meristem DOI PubMed
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NEW PHYTOLOGIST
Overexpression of lpxT gene in Escherichia coli inhibits cell division and causes envelope defects without changing the overall phosphorylation level of lipid A DOI PubMed
Falchi FA, Di Lorenzo F, Pizzoccheri R, Casino G, Paroni M, Forti F, Molinaro A, Briani F
Microorganisms
"Laniakea: an open solution to provide Galaxy “on-demand” instances over heterogeneous cloud infrastructures DOI PubMed
Marco Antonio Tangaro, Giacinto Donvito, Marica Antonacci, Matteo Chiara, Pietro Mandreoli, Graziano Pesole, Federico Zambelli
GigaScience
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Matteo Chiara, Pietro Mandreoli, Marco Antonio Tangaro, Anna Maria D’Erchia, Sandro Sorrentino, Cinzia Forleo, David S. Horner, Federico Zambelli, Graziano Pesole
Bioinformatics
CorGAT: a tool for the functional annotation of SARS-CoV-2 genomes DOI PubMed
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Bioinformatics
The Importance of Cytokinins during Reproductive Development in Arabidopsis and Beyond DOI PubMed
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International Journal of Molecular Science
2019
New roles of NO TRANSMITTING TRACT and SEEDSTICK during medial domain development in Arabidopsis fruits. DOI PubMed AIRHerrera-Ubaldo H, Lozano-Sotomayor P, Ezquer I, Di Marzo M, Chávez Montes RA, Gómez-Felipe A, Pablo-Villa J, Diaz-Ramirez D, Ballester P, Ferrándiz C, Sagasser M, Colombo L, Marsch N and de Folter S.
Development
Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State DOI PubMed AIR
Visconti L., Malagrinò F., Broggini L., De Luca CMG., Moda F., Gianni S., Ricagno S., Toto A.
International Journal of Molecular Sciences
Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect DOI PubMed
Niccolò Morè, Alessandra M. Martorana, Jacob Biboy, Christian Otten, Matthias Winkle, Carlos K. Gurnani Serrano, Alejandro Montón Silva, Lisa Atkinson, Hamish Yau, Eefjan Breukink, Tanneke den Blaauwe
mBio
A transcription factor coordinating internode elongation and photoperiodic signals in rice DOI PubMed AIR
Gómez-Ariza J, Brambilla V, Vicentini G, Landini M, Cerise M, Carrera E, Shrestha R, Chiozzotto R, Galbiati F, Caporali E, López Díaz I, Fornara F.
Nature Plants
Biochemical and biophysical comparison of human and mouse beta‐2 microglobulin reveals the molecular determinants of low amyloid propensity DOI PubMed AIR
Achour A., Broggini L., Han X., Sun R., Santambrogio C., Buratto J., Visentin C., Barbiroli A., De Luca C., Sormanni P., Moda F., De Simone A., Sandalova T., Grandori R., Camilloni C., Ricagno S.
The FEBS journal
High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion. DOI PubMed
Bollati M., Scalone E., Bonì F., Mastrangelo E., Giorgino T., Milani M. and De Rosa M.
Biochemical and Biophysical Research Communications
An alternative non-proteolytic mechanism may underlie AGel amyloidosis DOI PubMed
Bonì F., Milani M., Mastrangelo E., Barbiroli A., Diomede L. and De Rosa M.
Amyloid
Monitoring vitamin B12 in women treated with metformin for primary prevention of breast cancer and a DOI AIR
A. Mastroianni, C.M. Ciniselli, R. Panella, A. Macciotta, A. Cavalleri, E. Venturelli, F. Taverna, A
NUTRIENTS
Transmembrane chloride intracellular channel 1 (tmCLIC1) correlates with metastatic potential of col DOI AIR
V. Carlini, F. Cianci, I. Verduci, M. Mazzanti
CANCER RESEARCH
Chimeric HCN Channels for Studying cAMP-Induced Conformational Changes in the C-Linker DOI AIR
B. Introini, A. Saponaro, A. Bonicci, O. Rauh, F. Cantini, L. Banci, G. Thiel, A. Moroni
BIOPHYSICAL JOURNAL
NF-YA enters cells through cell penetrating peptides DOI AIR
D. Libetti, A. Bernardini, M.L. Chiaramonte, M. Minuzzo, N. Gnesutta, G. Messina, D. Dolfini, R. Man
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
RNase H activities counteract a toxic effect of Polymerase in cells replicating with depleted dNTP DOI PubMed AIR
A. Meroni, G.M. Nava, E. Bianco, L. Grasso, E. Galati, M.C. Bosio, D. Dalmastro, M. Muzi Falconi, F.
NUCLEIC ACIDS RESEARCH
Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled DOI AIR
M. Proietti, P. Agosti, C. Lonati, S. Corrao, F. Perticone, P.M. Mannucci, A. Nobili, S. Harari, M.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
Modulating the cardiotoxic behaviour of immunoglobulin light chain dimers through point mutations DOI AIR
M. Maritan, A. Ambrosetti, L. Oberti, A. Barbiroli, L. Diomede, M. Romeo, F. Lavatelli, P. Sormanni,
AMYLOID
The concurrency of several biophysical traits links immunoglobulin light chains with toxicity in AL DOI AIR
L. Oberti, M. Maritan, P. Rognoni, A. Barbiroli, F. Lavatelli, R. Russo, G. Palladini, M. Bolognesi,
AMYLOID
Developing Synthetic Peptides to Regulate Native HCN Channels DOI AIR
A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, V. Maione, M. Laskowski, P. Mesirca, M
BIOPHYSICAL JOURNAL
PLEIOTROPIC PHENOTYPE OF PSEUDOMONAS AERUGINOSA MUTANTS DEFECTIVE IN GLUCOSE UPTAKE DOI AIR
M. Raneri
STRATEGIES FOR AN OPTOGENETIC MODULATION OF THE PACEMAKER CURRENT IF DOI AIR
P. Zuccolini
The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties DOI PubMed
Matteo de Rosa, Alberto Barbiroli, Francesco Bonì, Emanuele Scalone, Davide Mattioni, Maria A. Vanoni, Marco Patrone, Michela Bollati, Eloise Mastrangelo, Toni Giorgino, Mario Milani
European Biophysics Journal
High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion. DOI PubMed
Michela Bollati, Emanuele Scalone, Francesco Bonì, Eloise Mastrangelo, Toni Giorgino, Mario Milani, Matteo de Rosa
Biochemical and Biophysical Research Communications
NF-YA Overexpression in Lung Cancer: LUSC DOI PubMed
Bezzecchi E, Ronzio M, Dolfini D, Mantovani R
Genes
GUN1 influences the accumulation of NEP‐dependent transcripts and chloroplast protein import in Arabidopsis cotyledons upon perturbation of chloroplast protein homeostasis DOI PubMed
Luca Tadini, Carlotta Peracchio, Andrea Trotta, Monica Colombo, Ilaria Mancini, Nicolaj Jeran, Alex Costa, Franco Faoro Milena Marsoni, Candida Vannini, Eva‐Mari Aro, Paolo Pesaresi
The Plant Journal
REM34 and REM35 Control Female and Male Gametophyte Development in Arabidopsis thaliana DOI PubMed
Caselli F, Beretta VM, Mantegazza O, Petrella R, Leo G, Guazzotti A, Herrera-Ubaldo H, de Folter S, Mendes MA, Kater MM, Gregis V.
Front Plant Sci.
Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant DOI PubMed
Giorgino T, Mattioni D, Hassan A, Milani M, Mastrangelo E, Barbiroli A, Verhelle A, Gettemans J, Barzago MM, Diomede L, de Rosa M
Biochim Biophys Acta Mol Basis Dis
Genetic insights into the modification of the pre-fertilization mechanisms during plant domestication DOI PubMed
Silvia Manrique, James Friel, Pietro Gramzio, Tomas Hasing, Ignazcio Ezquer, Aureliano Bombarely
Journal of Experimental Botany
REM34 and REM35 Control Female and Male Gametophyte Development in Arabidopsis thaliana DOI PubMed
Francesca Caselli, Veronica M. Beretta, Otho Mantegazza, Rosanna Petrella, Giulia Leo, Andrea Guazzotti, Humberto Herrera-Ubaldo, Stefan de Folter, Marta Adelina Mendes, Martin M. Kater, Veronica Gregis
Frontiers in Plant Science
2018
In Vivo Analysis of Calcium Levels and Glutathione Redox Status in Arabidopsis Epidermal Leaf Cells Infected with the Hypersensitive Response-Inducing Bacteria Pseudomonas syringae pv. tomato AvrB (PstAvrB). DOI PubMedDoccula FG, Luoni L, Behera S, Bonza MC, Costa A.
Methods Mol Biol. 2018;1743:125-141
RhoA and ERK Signalling Regulate the Expression of the Transcription Factor Nfix in Myogenic Cells DOI PubMed
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Development
Time-course transcriptome analysis of Arabidopsis siliques discloses genes essential for fruit development and maturation DOI PubMed AIR
Chiara Mizzotti, Lisa Rotasperti, Marco Moretto, Luca Tadini, Francesca Resentini, Bianca Galliani, Massimo Galbiati, Kristoff Engelen, Paolo Pesaresi, Simona Masiero
Plant Physiology
Backbone-Free Duplex-Stacked Monomer Nucleic Acids Exhibiting Watson-Crick Selectivity DOI PubMed AIR
Gregory P. Smith, Tommaso P. Fraccia, Marco Todisco, Giuliano Zanchetta, Chenhui Zhu, Emily Hayden, Tommaso Bellini, and Noel A. Clark
PNAS
Phase separations, liquid crystal ordering and molecular partitioning in mixtures of PEG and DNA oligomers DOI PubMed AIR
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Liquid Crystals
Nonenzymatic Polymerization into Long Linear RNA Templated by Liquid Crystal Self-Assembly DOI PubMed AIR
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ACS Nano
RhoA and ERK signalling regulate the expression of the transcription factor Nfix in myogenic cells DOI PubMed AIR
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Frontiers Genet
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nu DOI AIR
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ELIFE
Measuring the levels of ribonucleotides embedded in genomic DNA DOI AIR
A. Meroni, M. Nava Giulia, S. Sertic, P. Plevani, M. Muzi-Falconi, F. Lazzaro
A light-gated potassium channel for sustained neuronal inhibition DOI AIR
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NATURE METHODS
Assigning Function to the D and E Helices of HCN CNBD DOI AIR
A. Saponaro, A. Porro, C. Donadoni, B. Santoro, G. Thiel, A. Moroni
BIOPHYSICAL JOURNAL
Pseudomonas aeruginosa mutants defective in glucose uptake have pleiotropic phenotype and altered vi DOI AIR
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SCIENTIFIC REPORTS
A polysome-based microRNA screen identifies miR-24-3p as a novel pro-migratory miRNA in mesothelioma DOI AIR
S. Oliveto, R. Alfieri, A. Miluzio, A. Scagliola, R.S. Secl?, P. Gasparini, S. Grosso, L. Cascione,
CANCER RESEARCH
Translating the Game: Ribosomes as Active Players DOI AIR
P. Calamita, G. Gatti, A. Miluzio, A. Scagliola, S. Biffo
FRONTIERS IN GENETICS
Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation DOI PubMed
Roberto Imberti, Maria Lisa Garavaglia, Ivan Verduci, Gaetano Cannavale, Giorgio Balduzzi, Sara Papetti, Michele Mazzanti
Respiratory Research
2017
Designing Probes for Immunodiagnostics: Structural Insights into an Epitope Targeting Burkholderia Infections DOI PubMedCapelli R, Matterazzo E, Amabili M, Peri C, Gori A, Gagni P, Chiari M, Lertmemongkolchai G, Cretich M, Bolognesi M, Colombo G, Gourlay LJ
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Environ Microbiol. 2017 Oct;19(10):4220-4237. doi: 10.1111/1462-2920.13886. Epub 2017 Sep 15.
Mutation and suppressor analysis of the essential LPS-transport protein LptA reveals strategies to overcome severe outer membrane permeability defects in Escherichia coli DOI PubMed
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A capture method based on the VC1 domain reveals new binding properties of the human receptor for advanced glycation end products (RAGE) DOI PubMed
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The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p DOI PubMed
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DNAJC12 and dopa-responsive nonprogressive parkinsonism DOI PubMed
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CRP1 Protein: (dis)similarities between Arabidopsis thaliana and Zea mays. DOI PubMed
Ferrari R, Tadini L, Moratti F, Lehniger MK, Costa A, Rossi F, Colombo M, Masiero S, Schmitz-Linneweber C, Pesaresi P.
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Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor. DOI PubMed
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Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins DOI PubMed AIR
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Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity DOI PubMed AIR
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Antagonistic Transcription Factor Complexes Modulate the Floral Transition in Rice DOI PubMed AIR
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The Importance of Being on Time: Regulatory Networks Controlling Photoperiodic Flowering in Cereals DOI PubMed AIR
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Frontiers in Plant Science
Network-guided modelling allows tumor-type independent prediction of sensitivity to all-trans retinoic acid. DOI PubMed
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Annals of Oncology
DIFFERENTIATION OF HUMAN TELENCEPHALIC PROGENITOR CELLS INTO MSNS BY INDUCIBLE EXPRESSION OF GSX2 AND EBF1 DOI PubMed AIR
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PNAS
Exploring new pharmacological perspectives of Fusicoccin, a stabilizer of 14-3-3 ? target protein co DOI AIR
A. Saponaro, A. Porro, A.C. Sanjuan, B. Introini, M. Nardini, G. Thiel, A. Moroni
BIOPHYSICAL JOURNAL
In search of the transcriptional blueprints of a competent oocyte DOI AIR
R. Pasquariello, V. Bocchi, T. Brevini, F. Gandolfi
ANIMAL REPRODUCTION
The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Network DOI AIR
K. Clarke, S. Ricciardi, T. Pearson, I. Bharudin, P.K. Davidsen, M. Bonomo, D. Brina, A. Scagliola,
CELL REPORTS
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and DOI AIR
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DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system c DOI AIR
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DATA IN BRIEF
Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein DOI PubMed
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Human Molecular Genetics
2016
The Lack of the Essential LptC Protein in the Trans-Envelope Lipopolysaccharide Transport Machine Is Circumvented by Suppressor Mutations in LptF, an Inner Membrane Component of the Escherichia coli Transporter DOI PubMedBenedet M, Falchi FA, Puccio S, Di Benedetto C, Peano C, Polissi A, Dehò G.
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Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin DOI PubMed
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Int J Biomater. 2016;2016:8043983. doi: 10.1155/2016/8043983. Epub 2016 May 8.
Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking ?(1,3)-glucan remodeling DOI PubMed
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ABA-dependent control of GIGANTEA signalling enables drought escape via up-regulation of FLOWERING LOCUS T in Arabidopsis thaliana DOI PubMed
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A novel role for STOMATAL CARPENTER 1 in stomata patterning DOI PubMed
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Whole-gene CFTR sequencing combined with digital RT-PCR improves genetic diagnosis of cystic fibrosis. DOI PubMed
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PGR5-PGRL1-Dependent Cyclic Electron Transport Modulates Linear Electron Transport Rate in Arabidopsis thaliana. DOI PubMed
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Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant. DOI PubMed
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Seed abscission and fruit dehiscence required for seed dispersal rely on similar genetic networks DOI PubMed AIR
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Development
Searching for the in vivo transcriptome blueprint of competent bovine oocytes DOI AIR
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REPRODUCTION FERTILITY AND DEVELOPMENT
GUN1, a Jack-Of-All-Trades in Chloroplast Protein Homeostasis and Signaling DOI AIR
M. Colombo, L. Tadini, C. Peracchio, R. Ferrari, P. Pesaresi
FRONTIERS IN PLANT SCIENCE
2015
A covalent homodimer probing early oligomers along amyloid aggregation DOI PubMedHalabelian L, Relini A, Barbiroli A, Penco A, Bolognesi M, Ricagno S.
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An improved expression system for the VC1 ligand binding domain of the receptor for advanced glycation end products in Pichia pastoris DOI PubMed
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Protein Expr Purif. 2015 Oct;114:48-57. doi: 10.1016/j.pep.2015.06.012. Epub 2015 Jun 25 PMID:26118699
Catalytic properties of Phr family members of cell wall glucan remodeling enzymes: implications for the adaptation of Candida albicans to ambient pH DOI PubMed
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FEMS Yeast Res. 2015 Mar;15(2). pii: fou011. doi: 10.1093/femsyr/fou011. Epub 2015 Mar 10 PMID:25757890
The expanding spectrum of PRPS1-associated phenotypes: three novel mutations segregating with X-linked hearing loss and mild peripheral neuropathy. DOI PubMed
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Two novel splicing mutations in the SLC45A2 gene cause Oculocutaneous Albinism Type IV by unmasking cryptic splice sites DOI PubMed
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Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD(+)/H Binding to Mitochondrial Apoptosis-Inducing Factor. DOI PubMed
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Prediction of Antigenic B and T Cell Epitopes via Energy Decomposition Analysis: Description of the Web-Based Prediction Tool BEPPE DOI PubMed
Peri C, Solé OC, Corrada D, Gori A, Daura X, Colombo G
Methods Mol Biol. 2015;1348:13-22. doi: 10.1007/978-1-4939-2999-3_3
A whole-cell assay for specific inhibitors of translation initiation in bacteria DOI AIR
M. Raneri, B. Sciandrone, F. Briani
JOURNAL OF BIOMOLECULAR SCREENING
Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation DOI AIR
T. Touvier, C. De Palma, E. Rigamonti, A. Scagliola, E. Incerti, L. Mazelin, J. Thomas, M. D'Antonio
CELL DEATH & DISEASE
2014
Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic β2-microglobulin DOI PubMedHalabelian L, Ricagno S, Giorgetti S, Santambrogio C, Barbiroli A, Pellegrino S, Achour A, Grandori R, Marchese L, Raimondi S, Mangione PP, Esposito G, Al-Shawi R, Simons JP, Speck I, Stoppini M, Bolognesi M, Bellotti V.
J Biol Chem. 2014 Feb 7;289(6):3318-27. doi: 10.1074/jbc.M113.524157. Epub 2013 Dec 13.
A shotgun antisense approach to the identification of novel essential genes in Pseudomonas aeruginosa DOI PubMed
Rusmini R, Vecchietti D, Macchi R, Vidal-Aroca F, Bertoni G.
BMC Microbiol. 2014 Feb 5;14:24. doi: 10.1186/1471-2180-14-24.
Tet-Trap, a genetic approach to the identification of bacterial RNA thermometers: application to Pseudomonas aeruginosa DOI PubMed
Delvillani F, Sciandrone B, Peano C, Petiti L, Berens C, Georgi C, Ferrara S, Bertoni G, Pasini ME, Dehò G, Briani F.
RNA. 2014 Dec;20(12):1963-76. doi: 10.1261/rna.044354.114. Epub 2014 Oct 21 PMID:25336583
PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases DOI PubMed
Croci R, Tarantino D, Milani M, Pezzullo M, Rohayem J, Bolognesi M, Mastrangelo E.
FEBS Lett. 2014 May 2;588(9):1720-5. doi: 10.1016/j.febslet.2014.03.021. Epub 2014 Mar 18.
Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds DOI PubMed
Croci R, Pezzullo M, Tarantino D, Milani M, Tsay SC, Sureshbabu R, Tsai YJ, Mastrangelo E, Rohayem J, Bolognesi M, Hwu JR.
PLoS One. 2014 Mar 12;9(3):e91765. doi: 10.1371/journal.pone.0091765.
Effect of cytosolic pH on inward currents reveals structural characteristics of the proton transport cycle in the influenza A protein M2 in cell-free membrane patches of Xenopus oocytes DOI PubMed
DiFrancesco ML, Hansen UP, Thiel G, Moroni A, Schroeder I.
PLoS One. 2014 Sep 11;9(9):e107406. doi: 10.1371/journal.pone.0107406. eCollection 2014.
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function DOI PubMed
Saponaro A, Pauleta SR, Cantini F, Matzapetakis M, Hammann C, Donadoni C, Hu L, Thiel G, Banci L, Santoro B, Moroni A.
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14577-82. doi: 10.1073/pnas.1410389111. Epub 2014 Sep 2.
Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness DOI PubMed
Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Schroeder I, Simmons K, Aquila M, DiFrancesco D, Bolognesi M, Schwede F, Kashin D, Fishwick CW, Johnson AP, Thiel G, Moroni A.
Nat Chem Biol. 2014 Jun;10(6):457-62. doi: 10.1038/nchembio.1521.
hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3'-UTR and oppositely regulate its expression DOI PubMed
Zuccotti P, Colombrita C, Moncini S, Barbieri A, Lunghi M, Gelfi C, De Palma S, Nicolin A, Ratti A, Venturin M, Riva P.
Biochim Biophys Acta. 2014 Jun;1839(6):506-16. doi: 10.1016/j.bbagrm.2014.04.018. Epub 2014 May 2 PMID:24792867
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