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De Novo Assembly of the Polyhydroxybutyrate (PHB) Producer Azohydromonas lata Strain H1 Genome and Genomic Analysis of PHB Production Machinery DOI PubMedDaniele Traversa, Carlo Pazzani, Pietro D’Addabbo, Lucia Trisolini, Matteo Chiara, Marta Oliva, Angelo Marzella, Camilla Mandorino, Carla Calia, Guglielmina Chimienti, Caterina Manzari, Graziano Pesole, Maria Scrascia
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mapPat: tracking pathogens evolution in space and time DOI PubMed
Erika Ferrandi, Graziano Pesole, Matteo Chiara
Bioinformatics Advances
Shared molecular, cellular, and environmental hallmarks in cardiovascular disease and cancer: Any place for drug repurposing? DOI PubMed
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Mutations in HEADING DATE 1 affect transcription and cell wall composition in rice DOI PubMed
Marco Biancucci, Daniele Chirivì, Alessio Baldini, Eugene Badenhorst, Fabio Dobetti, Bahman Khahani, Elide Formentin, Tenai Eguen, Franziska Turck, John P Moore, Elahe Tavakol, Stephan Wenkel, Fiorella Lo Schiavo, Ignacio Ezquer, Vittoria Brambilla, David Horner, Matteo Chiara, Giorgio Perrella, Camilla Betti, Fabio Fornara
Plant Physiology
The generation of novel epialleles in plants: the prospective behind re-shaping the epigenome DOI PubMed
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Frontiers in Plant Science
Preventive Effect of Upland Pigmented Potatoes Against LPS-Induced Inflammation in THP-1 Macrophages DOI PubMed
Marta Toccaceli, Alessandra Marinelli, Federico Ballabio, Laura Bassolino, Roberto Lo Scalzo, Bruno Parisi, Daniela Pacifico, Federica Nicoletti, Carlo Camilloni, Giuseppe Mandolino, Katia Petroni
Molecular Nutrition & Food Research
Mapping Cell Identity from scRNA-seq: A primer on computational methods DOI PubMed
Daniele Traversa and Matteo Chiara
Computational and Structural Biotechnology Journal
Dynamics of Multisystem Inflammatory Syndrome in Children (MIS-C) associated to COVID-19: steady severity despite declining cases and new SARS-CoV-2 variants-a single-center cohort study DOI PubMed
Thomas Carzaniga, Valeria Calcaterra, Luca Casiraghi, Tommaso Inzani, Stephana Carelli, Gabriele Del Castillo, Danilo Cereda, Gianvincenzo Zuccotti, Marco Buscaglia
European Journal of Pediatrics
Poly-γ-glutamic acid alleviates cytotoxicity and inflammation induced by pre-formed fibrils of α-synuclein in murine primary astrocytes DOI PubMed
Claudia Novello, Mattia Parati, Samanta Mazzetti, Oriana Rampoldi, Huseyin Berkcan Isilgan, Milo Jarno Basellini, Chiara M G De Luca, Arianna Ciullini, Ilaria L Dellarole, Alessandro Fantin, Isabella Russo, Brian L Johnston, Moira Paroni, Chiara Rolando, Fabio Moda, Gianni Pezzoli, Iza K Radecka, Graziella Cappelletti
International Journal of Biological Maromolecules
Extraction and encapsulation of purple corn cob anthocyanins into starch- and zein-based delivery systems DOI PubMed
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Behind phyllotaxis, within the meristem: a REM-ARF complex shapes inflorescence in Arabidopsis thaliana DOI PubMed
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Histone deacetylase complex 1 facilitates hypocotyl elongation by attenuating acetylation and transcription via a PIF4-dependent process DOI PubMed
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Cell Reports
The burning glass effect of water droplets triggers a high light-induced calcium response in the chloroplast stroma DOI PubMed
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Current Biology
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Biology Direct
The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic Escherichia coli and eradicates biofilm-embedded bacteria synergizing with β-lactams DOI PubMed
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Antimicrobial agents and chemotherapy
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Briefings in Bioinformatics
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Mitochondria-derived reactive oxygen species are the likely primary trigger of mitochondrial retrograde signaling in Arabidopsis DOI PubMed
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Current Biology
ALS' Perfect Storm: C9orf72-Associated Toxic Dipeptide Repeats as Potential Multipotent Disruptors of Protein Homeostasis DOI PubMed
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Cells
The ALOG domain defines a family of plant-specific transcription factors acting during Arabidopsis flower development DOI PubMed
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Calcium-Driven In Silico Inactivation of a Human Olfactory Receptor DOI PubMed
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Journal of Chemical Information and Modeling
Development of pollinated and unpollinated ovules in Ginkgo biloba: unravelling pollen's role in ovule tissue maturation DOI PubMed
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Journal of Experimental Botany
Serum antibody fingerprinting of SARS-CoV-2 variants in infected and vaccinated subjects by label-free microarray biosensor DOI PubMed
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Frontiers in Immunology
Site-directed mutagenesis reveals the interplay between stability, structure and enzymatic activity in RidA from Capra hircus DOI PubMed
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Protein Science
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PNAS
AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn's disease is suppressed by rfaP and ybaT deletion DOI PubMed
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Gut Microbes
Comparing GBA1‐Parkinson's disease and idiopathic Parkinson's disease: α‐Synuclein oligomers and synaptic density as biomarkers in the skin biopsy DOI PubMed
Samanta Mazzetti, Elena Contaldi, Milo Jarno Basellini, Claudia Novello, Alessandra Maria Calogero, Letizia Straniero, Federica Garrì, Valentina Ferri, Daniela Calandrella, Francesca Del Sorbo, Rosanna Asselta, Emanuele Cereda, Graziella Cappelletti, Ioannis Ugo Isaias, Gianni Pezzoli
Brain Pathology
Noninvasive In Planta Live Measurements of H2O2 and Glutathione Redox Potential with Fluorescent roGFPs-Based Sensors DOI PubMed
Stefano Buratti, Matteo Grenzi, Giorgia Tortora, Sara Paola Nastasi, Elisa Dell'Aglio, Andrea Bassi, Alex Costa
Methods in Molecular Biology
Nicotinic Acid Derivatives As Novel Noncompetitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment DOI PubMed
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ACS Medicinal Chemistry Letters
Reproductive development in Trithuria submersa (Hydatellaceae: Nymphaeales): the involvement of AGAMOUS‑like genes DOI PubMed
Silvia Moschin, Sebastiano Nigris, Elisabetta Ofer, Nicola Babolin, Adriana Chiappetta, Leonardo Bruno, Barbara Baldan
Planta - Springer
A missense mutation in the barley Xan-h gene encoding the Mg-chelatase subunit I leads to a viable pale green line with reduced daily transpiration rate DOI PubMed
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Plant Cell Reports
Nicotinic Acid Derivatives As Novel Non-competitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment DOI PubMed
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ACS Medicinal Chemistry Letters
AA amyloidosis in vertebrates: epidemiology, pathology and molecular aspects DOI PubMed
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Amyloid, The Journal of Protein Folding Disorders
Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis DOI PubMed
Tim Schulte, Antonio Chaves-Sanjuan, Valentina Speranzini, Kevin Sicking, Melissa Milazzo, Giulia Mazzini, Paola Rognoni, Serena Caminito, Paolo Milani, Chiara Marabelli, Alessandro Corbelli, Luisa Diomede, Fabio Fiordaliso, Luigi Anastasia, Carlo Pappone, Giampaolo Merlini, Martino Bolognesi, Mario Nuvolone, Rubén Fernández-Busnadiego, Giovanni Palladini, Stefano Ricagno
Nature Communications
Integrating single nuclei and bulk RNA sequencing in rice shoot apical meristems uncovers candidate early floral transition gene networks DOI PubMed
Daniele Traversa, Giulio Vicentini, Paolo Korwin Krukowski, Lucio Conti, Matteo Chiara, Vittoria Brambilla
Plant Reprod 38
When repetita no-longer iuvant: somatic instability of the CAG triplet in Huntington’s disease DOI PubMed
Elena Cattaneo, Davide Scalzo, Martina Zobel, Raffaele Iennaco, Camilla Maffezzini, Dario Besusso, Simone Maestri
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Apomixis at high resolution: unravelling diplospory in Asteraceae DOI PubMed
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Journal of Experimental Botany
MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet DOI PubMed
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A PDZ tandem repeat folds and unfolds via different pathways DOI PubMed
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Protein Science
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ACS Publications
Separation of function mutants underline multiple roles of the Srs2 helicase/translocase in break-induced replication in Saccharomyces cerevisiae DOI PubMed
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MICROPUBLICATION BIOLOGY
Estimation of Ligand Binding Free Energy Using Multi-eGO Article link copied! DOI
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Journal of Chemical Information and Modeling
A PDZ tandem repeat folds and unfolds via different pathways DOI
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Protein Science
Nicotinic Acid Derivatives As Novel Non competitiveα‑Amylase and α‑GlucosidaseInhibitorsforType2DiabetesTreatment DOI PubMed
Andrea Citarella, Miriam Cavinato, Elena Rosini, Haidi Shehi, Federico Ballabio, Carlo Camilloni, Valerio Fasano, Alessandra Silvani, Daniele Passarella, Loredanoo Pollegioni, Marco Nardini.
ACS Medicinal Chemistry Letters
Allostery in homodimeric SARS-CoV-2 main protease DOI PubMed
Emanuele Fornasier*, Simone Fabbian*, Haidi Shehi, Janine Enderle, Barbara Gatto, Daniele Volpin, Barbara Biondi, Massimo Bellanda, Gabriele Giachin, Alice Sosic e Roberto Battistutta.
Comunication Biology
AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn's disease is suppressed by rfaP and ybaT deletion DOI PubMed
G Leccese, M Chiara, I Dusetti, D Noviello, E Billard, A Bibi, G Conte, C Consolandi, M Vecchi, M P Conte, N Barnich, F Caprioli, F Facciotti, M Paroni
Gut Microbes
The Paradox of Ribosomal Insufficiency Coupled with Increased Cancer: Shifting the Perspective from the Cancer Cell to the Microenvironment DOI PubMed
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Cancers (Basel)
Breaking Barriers: Exploiting Envelope Biogenesis and Stress Responses to Develop Novel Antimicrobial Strategies in Gram-Negative Bacteria DOI
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Pathogens
2023
Targeting the LPS export pathway for the development of novel therapeutics DOI PubMedSperandeo P, Martorana AM, Zaccaria M, Polissi A.
Biochim Biophys Acta Mol Cell Res.
Asexual reproduction through seeds: the complex case of diplosporous apomixis DOI PubMed
Letizia Cornaro, Camilla Banfi, Mara Cucinotta, Lucia Colombo, Peter J van Dijk
Journal of Experimental Botany
Two florigens and a florigen-like protein form a triple regulatory module at the shoot apical meristem to promote reproductive transitions in rice DOI PubMed
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Nature Plants
A missing piece in the control of rice flowering and inflorescence determinacy DOI PubMed
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Nature Plants
Human PNPase causes RNA stabilization and accumulation of R-loops in the Escherichia coli model system DOI PubMed
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Scientific Reports
Low antimicrobial resistance in Escherichia coli isolates from two large Austrian alpine karstic spring catchments DOI PubMed
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Science of The Total Environment
NF-YAl drives EMT in Claudinlow tumours DOI PubMed
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Cell Death & Disease
Accurate and Efficient SAXS/SANS Implementation Including Solvation Layer Effects Suitable for Molecular Simulations DOI PubMed
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Journal of Chemical Theory and Computation
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 DOI PubMed
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Cancer Communications
Long-distance turgor pressure changes induce local activation of plant glutamate receptor-like channels DOI PubMed
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Current Biology
Plant Ca2+-ATPases: From biochemistry to signalling DOI PubMed
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Biochimica Biophysica Acta. Molecular Cell Research
AMEBaS: Automatic Midline Extraction and Background Subtraction of Ratiometric Fluorescence Time-Lapses of Polarized Single Cells DOI PubMed
Rafael Badain, Daniel S C Damineli, Maria Teresa Portes, José Feijó, Stefano Buratti, Giorgia Tortora, Hugo Neves de Oliveira, Roberto M Cesar Jr
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A novel on-a-chip system with a 3D-bioinspired gut mucus suitable to investigate bacterial endotoxins dynamics DOI PubMed
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Materials Today Bio
Bone marrow vasculature advanced in vitro models for cancer and cardiovascular research DOI PubMed
Marzia Campanile; Leonardo Bettinelli; Camilla Cerutti; Gaia Spinetti
Frontiers in Cardiovascular Medicine
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device DOI PubMed
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APL Bioengineering
Multi-eGO: Model Improvements toward the Study of Complex Self-Assembly Processes DOI PubMed
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Journal of Chemical Theory and Computation
The Cyclic Peptide G4CP2 Enables The Modulation Of Galactose Metabolism In Yeast By Interfering With Gal4 Transcriptional Activity DOI PubMed
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FRONTIERS IN MOLECULAR BIOSCIENCES
Multi- e GO: Model Improvements toward the Study of Complex Self-Assembly Processes DOI PubMed
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Journal of Chemical Theory and Computation
2022
Activity and Function in Human Cells of the Evolutionary Conserved Exonuclease Polynucleotide Phosphorylase DOI PubMedFalchi FA, Pizzoccheri R, Briani F.
International Journal of Molecular Sciences
L- to D-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics DOI PubMed
Ballabio F., Broggini L., Paissoni C., Han X., Peqini K., Sala B.M., Sun R., Sandalova T., Barbiroli A., Achour A., Pellegrino S., Ricagno S., Camilloni C.
ACS Omega
Inactivation of the Pyrimidine Biosynthesis pyrD Gene Negatively Affects Biofilm Formation and Virulence Determinants in the Crohn’s Disease-Associated Adherent Invasive Escherichia coli LF82 Strain DOI PubMed
Rossi Elio, Gabriella Leccese, Valerio Baldelli, Alessia Bibi, Emanuele Scalone, Carlo Camilloni, Moira Paroni, and Paolo Landini
Microorganisms
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution DOI PubMed
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PNAS
Cell wall modifications by α-XYLOSIDASE1 are required for control of seed and fruit size in Arabidopsis DOI PubMed
Maurizio Di Marzo, Vívian Ebeling Viana, Camilla Banfi, Valeria Cassina, Roberta Corti, Humberto Herrera-Ubaldo, Nicola Babolin, Andrea Guazzotti, Edward Kiegle, Veronica Gregis, Stefan de Folter, Javier Sampedro, Francesco Mantegazza, Lucia Colombo, and Ignacio Ezquer
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Synthesis and Characterization of Curcumin-Loaded Nanoparticles of Poly(Glycerol Sebacate): A Novel Highly Stable Anticancer System DOI PubMed
Alessio Massironi, Stefania Marzorati, Alessandra Marinelli, Marta Toccaceli, Stefano Gazzotti, Marco Aldo Ortenzi, Daniela Maggioni, Katia Petroni, Luisella Verotta
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Pathogen Adaptation to American (Rpv3-1) and Eurasian (Rpv29) Grapevine Loci Conferring Resistance to Downy Mildew DOI PubMed
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Proceedings of the National Academy of Sciences
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Apis mellifera RidA, a novel member of the canonical YigF/YER057c/UK114 imine deiminase superfamily of enzymes pre-empting metabolic damage DOI PubMed
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Biochemical and Biophysical Research Communications
Lack of Direct Correlation between Biofilm Formation and Antimicrobial Resistance in Clinical Staphylococcus epidermidis Isolates from an Italian Hospital DOI PubMed
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Microorganisms
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Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery DOI PubMed
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Molecular Therapy
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila DOI PubMed
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Cell Death and Disease
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Journal of Tissue Engineering
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NF-Y Subunits Overexpression in HNSCC DOI PubMed
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Molecular Plant
Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos DOI PubMed
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International Journal of Molecular Sciences
Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation DOI PubMed
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International Journal of Molecular Sciences
The transcription factor NF-Y participates to stem cell fate decision and regeneration in adult skeletal muscle DOI PubMed
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Nature Communications
From single cells to flowers – Biological complexity driving plant reproductive development DOI PubMed
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Preprints
Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients DOI PubMed
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Journal of Experimental & Clinical Cancer Research
Comparative Analysis of Genotyping by Sequencing and Whole-Genome Sequencing Methods in Diversity Studies of Olea europaea L DOI PubMed
James Friel, Aureliano Bombarely, Carmen Dorca Fornell, Francisco Luque, Ana Maria Fernández-Ocaña
Plants
NF-Y subunits overexpression in gastric adenocarcinomas (STAD) DOI PubMed
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Scientific Reports
VID22 counteracts G-quadruplex-induced genome instability DOI PubMed
E. Galati, M. C. Bosio, D. Novarina, M. Chiara, G. M. Bernini, A. M. Mozzarelli, M. L. García-Rubio, B. Gómez-González, A. Aguilera, T. Carzaniga, M. Todisco, T. Bellini, G. M. Nava, G. Frigè, et al.
Nucleic Acids Research
NF-Y subunits overexpression in gastric adenocarcinomas (STAD) DOI PubMed
Alberto Gallo, Mirko Ronzio, Eugenia Bezzecchi, Roberto Mantovani & Diletta Dolfini
Scientific Reports
Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles DOI PubMed
Valentina Fajner, Fabio Giavazzi, Simona Sala, Amanda Oldani, Emanuele Martini, Francesco Napoletano, Dario Parazzoli, Giuliana Cesare, Roberto Cerbino, Elena Maspero, Thomas Vaccari & Simona Polo
Nature Communications
Long COVID: long-term effects? DOI PubMed
Di Toro A, Bozzani A, Tavazzi G, Urtis M, Giuliani L, Pizzoccheri R, Aliberti F, Fergnani V, Arbustini E.
European Heart Journal, Supplements
Laniakea@ReCaS: exploring the potential of customisable Galaxy on-demand instances as a cloud-based service DOI PubMed
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bmc-bioinformatics
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Folia microbiologica
”Ascan: a novel method for the study of inter-individual allele specific expression DOI PubMed
Federico Zambelli, Matteo Chiara, Erika Ferrandi, Pietro Mandreoli, Marco Antonio Tangaro, Giulio Pavesi, Graziano Pesole
Journal of molecular biology
Targeted knockout of the gene OsHOL1 removes methyl iodide emissions from rice plants DOI PubMed
Martina Carlessi, Lorenzo Mariotti, Francesca Giaume, Fabio Fornara, Pierdomenico Perata, Silvia Gonzali
Scientific Reports
Anthocyanins: From Mechanisms of Regulation in Plants to Health Benefits in Foods DOI PubMed
Francesca Cappellini, Alessandra Marinelli, Marta Toccaceli, Chiara Tonelli, Katia Petroni
Frontiers in Plant Science
Multi- and Transgenerational Outcomes of an Exposure to a Mixture of Endocrine-Disrupting Chemicals (EDCs) on Puberty and Maternal Behavior in the Female Rat DOI PubMed
David López-Rodríguez, Carlos Francisco Aylwin, Virginia Delli, Elena Sevrin, Marzia Campanile, Marion Martin, Delphine Franssen, Arlette Gérard, Silvia Blacher, Ezio Tirelli, Agnès Noël, Alejandro Lomniczi, Anne-Simone Parent
Environmental Health Perspectives
Synthetic Protein Circuits And Devices Based On Reversible Protein-Protein Interactions: An Overview DOI PubMed
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Life (MDPI)
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BPC Transcription Factors and a Polycomb Group Protein Confine the Expression of the Ovule Identity Gene SEEDSTICK in Arabidopsis DOI PubMedPetrella R., Caselli F., Roig-Villanova I., Vignati V., Chiara M., Ezquer I., Tadini L., Kater M. M., Gregis V.
The Plant Journal
Efficacy of Cholesterol Nose-to-Brain Delivery for Brain Targeting in Huntington's Disease DOI PubMed
Passoni A, Favagrossa M, Colombo L, Bagnati R, Gobbi M, Diomede L, Birolini G, Di Paolo E, Valenza M, Cattaneo E, Salmona M.
ACS Chemical Neuroscience
NF-YA Overexpression in Lung Cancer: LUAD DOI PubMed
Bezzecchi E, Ronzio M, Semeghini V, Andrioletti V, Mantovani R, Dolfini D
Genes
Integrating Peak Colocalization and Motif Enrichment Analysis for the Discovery of Genome-Wide Regulatory Modules and Transcription Factor Recruitment Rules DOI PubMed
Ronzio M, Zambelli F, Dolfini D, Mantovani R, Pavesi G.
Frontiers in genetics
Barley’s Second Spring as a Model Organism for Chloroplast DOI PubMed
Lisa Rotasperti,Francesca Sansoni,Chiara Mizzotti,Luca Tadini and Paolo Pesaresi
Plants
Rad9/53BP1 promotes DNA repair via crossover recombination by limiting the Sgs1 and Mph1 helicases DOI PubMed
Matteo Ferrari, Chetan C. Rawal, Samuele Lodovichi, Maria Y. Vietri & Achille Pellicioli
NATURE COMMUNICATION
Expression pattern of the small muscle protein, X-linked (smpx) gene during zebrafish embryonic and larval developmental stages DOI PubMed
Anna Ghilardi, Alberto Diana, Laura Prosperi, Luca Del Giacco
Gene Expression Patterns
Glycosylation Tunes Neuroserpin Physiological and Pathological Properties DOI PubMed
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International Journal of Molecular Sciences
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors DOI PubMed
Visentin C., Musso L., Broggini L., Bonato F., Russo R., Moriconi C., Bolognesi M., Miranda E., Dellavalle S., Passarella D., Ricagno S.
Life
Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive Escherichia coli (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease DOI PubMed
Gabriella Leccese, Alessia Bibi, Stefano Mazza, Federica Facciotti, Flavio Caprioli, Paolo Landini, Moira Paroni
Cells
Nutritional intervention with cyanidin hinders the progression of muscular dystrophy DOI PubMed
Saclier M, Bonfanti C, Antonini S, Angelini G, Mura G, Zanaglio F, Taglietti V, Romanello V, Sandri M, Tonelli C, Petroni K, Cassano M, Messina G
Cell Death & Disease
Missense mutations affecting Ca2+ coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties DOI PubMed
Giuditta Dal Cortivo, ValerioMarino, Francesco Bonì, MarioMilani and Daniele Dell'Orco
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Crop reproductive meristems in the genomic era: a brief overview. DOI PubMed
Caselli F, Zanarello F, Kater MM, Battaglia R, Gregis V
Biochem Soc Trans
Functionally Divergent Splicing Variants of the Rice AGAMOUS Ortholog OsMADS3 Are Evolutionary Conserved in Grasses. DOI PubMed
Dreni L, Ravasio A, Gonzalez-Schain N, Jacchia S, da Silva GJ, Ricagno S, Russo R, Caselli F, Gregis V and Kater MM
Front. Plant Sci
MADS-Box and bHLH Transcription Factors Coordinate Transmitting Tract Development in Arabidopsis thaliana. DOI PubMed
Di Marzo M, Roig-Villanova I, Zanchetti E, Caselli F, Gregis V, Bardetti P, Chiara M, Guazzotti A, Caporali E, Mendes MA, Colombo L and Kater MM
Front. Plant Sci
Light affects tissue patterning of the hypocotyl in the shade-avoidance response DOI PubMed
Esther Botterweg-Paredes, Anko Blaakmeer, Shin-Young Hong, Bin Sun, Lorenzo Mineri, Valdeko Kruusvee, Yakun Xie, Daniel Straub, Delphine Ménard, Edouard Pesquet, Stephan Wenkel
PLOS Genetics
The plastid transcription machinery and its coordination with the expression of nuclear genome: PEP, NEP and the GUN1-mediated retrograde communication DOI PubMed
Luca Tadini, Nicolaj Jeran, Carlotta Peracchio, Simona Masiero, Monica Colombo and Paolo Pesaresi
Philosophical Transactions of The Royal Society B Biological Sciences
Higher order photoprotection mutants reveal the importance of ΔpH-dependent photosynthesis-control in preventing light induced damage to both photosystem II and photosystem I DOI PubMed
Roberto Barbato, Luca Tadini, Romina Cannata, Carlotta Peracchio, Nicolaj Jeran, Alessandro Alboresi, Tomas Morosinotto, Azfar Ali Bajwa,Virpi Paakkarinen,Marjaana Suorsa, Eva-Mari Aro, Paolo Pesaresi
Scientific Reports
GUN1 and Plastid RNA Metabolism: Learning from Genetics DOI PubMed
Luca Tadini, Nicolaj Jeran, Paolo Pesaresi
Cells
Modulation of Guanylate Cyclase Activating Protein 1 (GCAP1) Dimeric Assembly by Ca2+ or Mg2+: Hints to Understand Protein Activity DOI PubMed
Francesco Bonì, Valerio Marino, Carlo Bidoia, Eloise Mastrangelo, Alberto Barbiroli, Daniele Dell'Orco and Mario Milani
Biomolecules
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis DOI PubMed
Muzio L, Sirtori R, Gornati D, Eleuteri S, Fossaghi A, Brancaccio D, Manzoni L, Ottoboni L, Feo L, Quattrini A, Mastrangelo E, Sorrentino L, Scalone E, Comi G, Marinelli L, Riva N, Milani M, Seneci P
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CLIC1 Protein Accumulates in Circulating Monocyte Membrane during Neurodegeneration DOI PubMed
Valentina Carlini, Ivan Verduci, Francesca Cianci, Gaetano Cannavale, Chiara Fenoglio, Daniela Galimberti, and Michele Mazzanti
International Journal of Molecular Sciences
RUES2 hESCs exhibit MGE-biased neuronal differentiation and muHTT-dependent defective specification hinting at SP1 DOI PubMed
Paola Conforti1,2, Dario Besusso1,2, Silvia Brocchetti1,2, Ilaria Campus1,2, Claudio Cappadona1,2, Maura Galimberti1,2, Angela Laporta1, Raffaele Iennaco1,2, Riccardo Rossi2, Vittoria Bocchi D.1,2, El
Neurobiology of Disease
Transcriptional dynamics of induced pluripotent stem cell differentiation into β cells reveals full endodermal commitment and homology with human islets DOI PubMed
Pellegrini S, Chimienti R, Scotti GM , Giannese F, Lazarevic D, Manenti F, Poggi G, Lombardo MT, Cospito A, Nano R, Piemonti L, Sordi V
Cytotherapy
One, No One, and One Hundred Thousand: The Many Forms of Ribonucleotides in DNA DOI PubMed
Giulia Maria Nava, Lavinia Grasso, Sarah Sertic, Achille Pellicioli, Marco Muzi Falconi, and Federico Lazzaro
International Journal of Molecular Sciences
Ethanol exposure increases mutation rate through error-prone polymerases DOI PubMed
Karin Voordeckers, Camilla Colding, Lavinia Grasso, et al.
Nature Communications
NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC) DOI PubMed
Bezzecchi E, Ronzio M, Mantovani R, Dolfini D
Int. J. Mol. Sc
IBDs and the pediatric age: Their peculiarities and the involvement of the microbiota DOI PubMed
Lucia Cococcioni, Simona Panelli, Ilaria Varotto-Boccazzi, Domenico Di Carlo, Dario Pistone, Gabriella Leccese, Gian Vincenzo Zuccotti, Francesco Comandatore
Digestive and Liver disease
On the NF-Y regulome as in ENCODE (2019). DOI PubMed
Ronzio M, Bernardini A, Pavesi G, Mantovani R, Dolfini D.
PLoS Computational Biology
The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action DOI PubMed
Bahare Salehi, Javad Sharifi-Rad, Francesca Cappellini, Željko Reiner, Debora Zorzan, Muhammad Imran, Bilge Sener, Mehtap Kilic, Mohamed El-Shazly, Nouran M Fahmy, Eman Al-Saye
Front Pharmacol
Tau and DNA Damage in Neurodegeneration DOI PubMed
Luca Colnaghi, Diego Rondelli, Marco Muzi-Falconi, Sarah Sertic
Brain Sciences
OsFD4 promotes the rice floral transition via florigen activation complex formation in the shoot apical meristem DOI PubMed
M. Cerise, F. Giaume, M. Galli, B. Khahani, J. Lucas, F. Podico, E. Tavakol, F. Parcy, A. Gallavotti, V.Brambilla, F. Fornara
NEW PHYTOLOGIST
Overexpression of lpxT gene in Escherichia coli inhibits cell division and causes envelope defects without changing the overall phosphorylation level of lipid A DOI PubMed
Falchi FA, Di Lorenzo F, Pizzoccheri R, Casino G, Paroni M, Forti F, Molinaro A, Briani F
Microorganisms
"Laniakea: an open solution to provide Galaxy “on-demand” instances over heterogeneous cloud infrastructures DOI PubMed
Marco Antonio Tangaro, Giacinto Donvito, Marica Antonacci, Matteo Chiara, Pietro Mandreoli, Graziano Pesole, Federico Zambelli
GigaScience
VINYL: Variant prIoritizatioN bY survivaL analysis DOI PubMed
Matteo Chiara, Pietro Mandreoli, Marco Antonio Tangaro, Anna Maria D’Erchia, Sandro Sorrentino, Cinzia Forleo, David S. Horner, Federico Zambelli, Graziano Pesole
Bioinformatics
CorGAT: a tool for the functional annotation of SARS-CoV-2 genomes DOI PubMed
Matteo Chiara,Federico Zambelli, Marco Antonio Tangaro, Pietro Mandreoli, David S. Horner and Graziano Pesole.
Bioinformatics
The Importance of Cytokinins during Reproductive Development in Arabidopsis and Beyond DOI PubMed
Giada Callizaya Terceros, Francesca Resentini, Mara Cucinotta, Silvia Manrique, Lucia Colombo and Marta A. Mendes
International Journal of Molecular Science
Senataxin Ortholog Sen1 Limits DNA:RNA Hybrid Accumulation at DNA Double-Strand Breaks to Control End Resection and Repair Fidelity DOI PubMed
M. Di Terlizzi;E. Galati;F. Lazzaro;G. Liberi;A. Pellicioli
CELL REPORTS
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New roles of NO TRANSMITTING TRACT and SEEDSTICK during medial domain development in Arabidopsis fruits. DOI PubMed AIRHerrera-Ubaldo H, Lozano-Sotomayor P, Ezquer I, Di Marzo M, Chávez Montes RA, Gómez-Felipe A, Pablo-Villa J, Diaz-Ramirez D, Ballester P, Ferrándiz C, Sagasser M, Colombo L, Marsch N and de Folter S.
Development
Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State DOI PubMed AIR
Visconti L., Malagrinò F., Broggini L., De Luca CMG., Moda F., Gianni S., Ricagno S., Toto A.
International Journal of Molecular Sciences
Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect DOI PubMed
Niccolò Morè, Alessandra M. Martorana, Jacob Biboy, Christian Otten, Matthias Winkle, Carlos K. Gurnani Serrano, Alejandro Montón Silva, Lisa Atkinson, Hamish Yau, Eefjan Breukink, Tanneke den Blaauwe
mBio
A transcription factor coordinating internode elongation and photoperiodic signals in rice DOI PubMed AIR
Gómez-Ariza J, Brambilla V, Vicentini G, Landini M, Cerise M, Carrera E, Shrestha R, Chiozzotto R, Galbiati F, Caporali E, López Díaz I, Fornara F.
Nature Plants
Biochemical and biophysical comparison of human and mouse beta‐2 microglobulin reveals the molecular determinants of low amyloid propensity DOI PubMed AIR
Achour A., Broggini L., Han X., Sun R., Santambrogio C., Buratto J., Visentin C., Barbiroli A., De Luca C., Sormanni P., Moda F., De Simone A., Sandalova T., Grandori R., Camilloni C., Ricagno S.
The FEBS journal
High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion. DOI PubMed
Bollati M., Scalone E., Bonì F., Mastrangelo E., Giorgino T., Milani M. and De Rosa M.
Biochemical and Biophysical Research Communications
An alternative non-proteolytic mechanism may underlie AGel amyloidosis DOI PubMed
Bonì F., Milani M., Mastrangelo E., Barbiroli A., Diomede L. and De Rosa M.
Amyloid
Monitoring vitamin B12 in women treated with metformin for primary prevention of breast cancer and a DOI AIR
A. Mastroianni, C.M. Ciniselli, R. Panella, A. Macciotta, A. Cavalleri, E. Venturelli, F. Taverna, A
NUTRIENTS
Transmembrane chloride intracellular channel 1 (tmCLIC1) correlates with metastatic potential of col DOI AIR
V. Carlini, F. Cianci, I. Verduci, M. Mazzanti
CANCER RESEARCH
Chimeric HCN Channels for Studying cAMP-Induced Conformational Changes in the C-Linker DOI AIR
B. Introini, A. Saponaro, A. Bonicci, O. Rauh, F. Cantini, L. Banci, G. Thiel, A. Moroni
BIOPHYSICAL JOURNAL
NF-YA enters cells through cell penetrating peptides DOI AIR
D. Libetti, A. Bernardini, M.L. Chiaramonte, M. Minuzzo, N. Gnesutta, G. Messina, D. Dolfini, R. Man
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
RNase H activities counteract a toxic effect of Polymerase in cells replicating with depleted dNTP DOI PubMed AIR
A. Meroni, G.M. Nava, E. Bianco, L. Grasso, E. Galati, M.C. Bosio, D. Dalmastro, M. Muzi Falconi, F.
NUCLEIC ACIDS RESEARCH
Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled DOI AIR
M. Proietti, P. Agosti, C. Lonati, S. Corrao, F. Perticone, P.M. Mannucci, A. Nobili, S. Harari, M.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
Modulating the cardiotoxic behaviour of immunoglobulin light chain dimers through point mutations DOI AIR
M. Maritan, A. Ambrosetti, L. Oberti, A. Barbiroli, L. Diomede, M. Romeo, F. Lavatelli, P. Sormanni,
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The concurrency of several biophysical traits links immunoglobulin light chains with toxicity in AL DOI AIR
L. Oberti, M. Maritan, P. Rognoni, A. Barbiroli, F. Lavatelli, R. Russo, G. Palladini, M. Bolognesi,
AMYLOID
Developing Synthetic Peptides to Regulate Native HCN Channels DOI AIR
A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, V. Maione, M. Laskowski, P. Mesirca, M
BIOPHYSICAL JOURNAL
PLEIOTROPIC PHENOTYPE OF PSEUDOMONAS AERUGINOSA MUTANTS DEFECTIVE IN GLUCOSE UPTAKE DOI AIR
M. Raneri
STRATEGIES FOR AN OPTOGENETIC MODULATION OF THE PACEMAKER CURRENT IF DOI AIR
P. Zuccolini
The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties DOI PubMed
Matteo de Rosa, Alberto Barbiroli, Francesco Bonì, Emanuele Scalone, Davide Mattioni, Maria A. Vanoni, Marco Patrone, Michela Bollati, Eloise Mastrangelo, Toni Giorgino, Mario Milani
European Biophysics Journal
High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion. DOI PubMed
Michela Bollati, Emanuele Scalone, Francesco Bonì, Eloise Mastrangelo, Toni Giorgino, Mario Milani, Matteo de Rosa
Biochemical and Biophysical Research Communications
NF-YA Overexpression in Lung Cancer: LUSC DOI PubMed
Bezzecchi E, Ronzio M, Dolfini D, Mantovani R
Genes
GUN1 influences the accumulation of NEP‐dependent transcripts and chloroplast protein import in Arabidopsis cotyledons upon perturbation of chloroplast protein homeostasis DOI PubMed
Luca Tadini, Carlotta Peracchio, Andrea Trotta, Monica Colombo, Ilaria Mancini, Nicolaj Jeran, Alex Costa, Franco Faoro Milena Marsoni, Candida Vannini, Eva‐Mari Aro, Paolo Pesaresi
The Plant Journal
REM34 and REM35 Control Female and Male Gametophyte Development in Arabidopsis thaliana DOI PubMed
Caselli F, Beretta VM, Mantegazza O, Petrella R, Leo G, Guazzotti A, Herrera-Ubaldo H, de Folter S, Mendes MA, Kater MM, Gregis V.
Front Plant Sci.
Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant DOI PubMed
Giorgino T, Mattioni D, Hassan A, Milani M, Mastrangelo E, Barbiroli A, Verhelle A, Gettemans J, Barzago MM, Diomede L, de Rosa M
Biochim Biophys Acta Mol Basis Dis
Genetic insights into the modification of the pre-fertilization mechanisms during plant domestication DOI PubMed
Silvia Manrique, James Friel, Pietro Gramzio, Tomas Hasing, Ignazcio Ezquer, Aureliano Bombarely
Journal of Experimental Botany
REM34 and REM35 Control Female and Male Gametophyte Development in Arabidopsis thaliana DOI PubMed
Francesca Caselli, Veronica M. Beretta, Otho Mantegazza, Rosanna Petrella, Giulia Leo, Andrea Guazzotti, Humberto Herrera-Ubaldo, Stefan de Folter, Marta Adelina Mendes, Martin M. Kater, Veronica Gregis
Frontiers in Plant Science
2018
In Vivo Analysis of Calcium Levels and Glutathione Redox Status in Arabidopsis Epidermal Leaf Cells Infected with the Hypersensitive Response-Inducing Bacteria Pseudomonas syringae pv. tomato AvrB (PstAvrB). DOI PubMedDoccula FG, Luoni L, Behera S, Bonza MC, Costa A.
Methods Mol Biol. 2018;1743:125-141
RhoA and ERK Signalling Regulate the Expression of the Transcription Factor Nfix in Myogenic Cells DOI PubMed
Taglietti V., Angelini G., Mura G., Bonfanti C., Caruso E., Monteverde S., Le Carrou G., Tajbakhsh S., Relaix F. and Messina G.
Development
Time-course transcriptome analysis of Arabidopsis siliques discloses genes essential for fruit development and maturation DOI PubMed AIR
Chiara Mizzotti, Lisa Rotasperti, Marco Moretto, Luca Tadini, Francesca Resentini, Bianca Galliani, Massimo Galbiati, Kristoff Engelen, Paolo Pesaresi, Simona Masiero
Plant Physiology
Backbone-Free Duplex-Stacked Monomer Nucleic Acids Exhibiting Watson-Crick Selectivity DOI PubMed AIR
Gregory P. Smith, Tommaso P. Fraccia, Marco Todisco, Giuliano Zanchetta, Chenhui Zhu, Emily Hayden, Tommaso Bellini, and Noel A. Clark
PNAS
Phase separations, liquid crystal ordering and molecular partitioning in mixtures of PEG and DNA oligomers DOI PubMed AIR
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Liquid Crystals
Nonenzymatic Polymerization into Long Linear RNA Templated by Liquid Crystal Self-Assembly DOI PubMed AIR
M Todisco, TP Fraccia, GP Smith, A Corno, L Bethge, S Klussmann, EM Paraboschi, R Asselta, D Colombo, G Zanchetta, NA Clark and T Bellini
ACS Nano
RhoA and ERK signalling regulate the expression of the transcription factor Nfix in myogenic cells DOI PubMed AIR
Taglietti V, Angelini G, Mura G, Bonfanti C, Caruso E, Monteverde S, Le Carrou G, Tajbakhsh S, Relaix F, Messina G.
Development
High MYC Levels Favour Multifocal Carcinogenesis DOI PubMed
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Frontiers Genet
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nu DOI AIR
A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, V. Maione, C. Donadoni, B. Introini, P
ELIFE
Measuring the levels of ribonucleotides embedded in genomic DNA DOI AIR
A. Meroni, M. Nava Giulia, S. Sertic, P. Plevani, M. Muzi-Falconi, F. Lazzaro
A light-gated potassium channel for sustained neuronal inhibition DOI AIR
L. Alberio, A. Locarno, A. Saponaro, E. Romano, V. Bercier, S. Albadri, F. Simeoni, S. Moleri, S. Pe
NATURE METHODS
Assigning Function to the D and E Helices of HCN CNBD DOI AIR
A. Saponaro, A. Porro, C. Donadoni, B. Santoro, G. Thiel, A. Moroni
BIOPHYSICAL JOURNAL
Pseudomonas aeruginosa mutants defective in glucose uptake have pleiotropic phenotype and altered vi DOI AIR
M. Raneri, E. Pinatel, C. Peano, G. Rampioni, L. Leoni, I. Bianconi, O. Jousson, C. Dalmasio, P. Fer
SCIENTIFIC REPORTS
A polysome-based microRNA screen identifies miR-24-3p as a novel pro-migratory miRNA in mesothelioma DOI AIR
S. Oliveto, R. Alfieri, A. Miluzio, A. Scagliola, R.S. Secl?, P. Gasparini, S. Grosso, L. Cascione,
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Translating the Game: Ribosomes as Active Players DOI AIR
P. Calamita, G. Gatti, A. Miluzio, A. Scagliola, S. Biffo
FRONTIERS IN GENETICS
Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation DOI PubMed
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Respiratory Research
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Designing Probes for Immunodiagnostics: Structural Insights into an Epitope Targeting Burkholderia Infections DOI PubMedCapelli R, Matterazzo E, Amabili M, Peri C, Gori A, Gagni P, Chiari M, Lertmemongkolchai G, Cretich M, Bolognesi M, Colombo G, Gourlay LJ
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Mutation and suppressor analysis of the essential LPS-transport protein LptA reveals strategies to overcome severe outer membrane permeability defects in Escherichia coli DOI PubMed
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A capture method based on the VC1 domain reveals new binding properties of the human receptor for advanced glycation end products (RAGE) DOI PubMed
Degani G, Altomare AA, Colzani M, Martino C, Mazzolari A, Fritz G, Vistoli G, Popolo L, Aldini G.
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The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p DOI PubMed
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Sci Rep. 2017 Oct 5;7(1):12702. doi: 10.1038/s41598-017-12973-5.
DNAJC12 and dopa-responsive nonprogressive parkinsonism DOI PubMed
Straniero L, Guella I, Cilia R, Parkkinen L, Rimoldi V, Young A, Asselta R, Soldà G, Sossi V, Stoessl AJ, Priori A, Nishioka K, Hattori N, Follett J, Rajput A, Blau N, Pezzoli G, Farrer MJ, Goldwurm S, Rajput AH, Duga S.
Ann Neurol. 2017 Oct;82(4):640-646. doi: 10.1002/ana.25048.
CRP1 Protein: (dis)similarities between Arabidopsis thaliana and Zea mays. DOI PubMed
Ferrari R, Tadini L, Moratti F, Lehniger MK, Costa A, Rossi F, Colombo M, Masiero S, Schmitz-Linneweber C, Pesaresi P.
Front Plant Sci. 2017 Feb 15;8:163. doi: 10.3389/fpls.2017.00163. eCollection 2017 PMID: 28261232
Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor. DOI PubMed
Sorrentino L, Cossu F, Milani M, Aliverti A, Mastrangelo E.
Biochem Biophys Res Commun. 2017 Aug 26;490(3):1011-1017. doi: 10.1016/j.bbrc.2017.06.156. Epub 2017 Jun 27.
Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins DOI PubMed AIR
Saponaro A, Porro A, Chaves-Sanjuan A, Nardini M, Rauh O, Thiel G, Moroni A.
Plant Cell. 2017 Oct;29(10):2570-2580. doi: 10.1105/tpc.17.00375. Epub 2017 Sep 29.
Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity DOI PubMed AIR
Oberti L, Rognoni P, Barbiroli A, Lavatelli F, Russo R, Maritan M, Palladini G, Bolognesi M, Merlini G, Ricagno S.
Sci Rep. 2017 Dec 1;7(1):16809. doi: 10.1038/s41598-017-16953-7.
Antagonistic Transcription Factor Complexes Modulate the Floral Transition in Rice DOI PubMed AIR
Vittoria Brambilla, Damiano Martignago, Daniela Goretti, Martina Cerise, Marc Somssich, Matteo de Rosa, Francesca Galbiati, Roshi Shrestha, Federico Lazzaro, Rüdiger Simon and Fabio Fornara
Plant Cell. Vol. 29: 2801–2816
The Importance of Being on Time: Regulatory Networks Controlling Photoperiodic Flowering in Cereals DOI PubMed AIR
Vittoria Brambilla, Jorge Gomez-Ariza, Martina Cerise, and Fabio Fornara
Frontiers in Plant Science
Network-guided modelling allows tumor-type independent prediction of sensitivity to all-trans retinoic acid. DOI PubMed
Bolis M, Garattini E, Paroni G, Zanetti A, Kurosaki M, Castrignano’ T, Garattini SK, Biancardi F, Barzago MM, Gianni’ M, Terao M, Pattini L, Fratelli M
Annals of Oncology
DIFFERENTIATION OF HUMAN TELENCEPHALIC PROGENITOR CELLS INTO MSNS BY INDUCIBLE EXPRESSION OF GSX2 AND EBF1 DOI PubMed AIR
Andrea Faedo, Angela Laporta, Alice Segnali, Maura Galimberti, Dario Besusso, Elisabetta Cesana, Sara Belloli, Rosa Maria Moresco, Marta Tropiano, Elisa Fucà, Stefan Wild, Andreas Bosio, Alessandro Ve
PNAS
Exploring new pharmacological perspectives of Fusicoccin, a stabilizer of 14-3-3 ? target protein co DOI AIR
A. Saponaro, A. Porro, A.C. Sanjuan, B. Introini, M. Nardini, G. Thiel, A. Moroni
BIOPHYSICAL JOURNAL
In search of the transcriptional blueprints of a competent oocyte DOI AIR
R. Pasquariello, V. Bocchi, T. Brevini, F. Gandolfi
ANIMAL REPRODUCTION
The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Network DOI AIR
K. Clarke, S. Ricciardi, T. Pearson, I. Bharudin, P.K. Davidsen, M. Bonomo, D. Brina, A. Scagliola,
CELL REPORTS
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and DOI AIR
N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, D. Brina, T. Adler, D.H. B
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system c DOI AIR
N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, T. Adler, D.H. Busch, V. G
DATA IN BRIEF
Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein DOI PubMed
Francesco Bonì, Mario Milani, Alberto Barbiroli, Luisa Diomede, Eloise Mastrangelo and Matteo de Rosa
Human Molecular Genetics
2016
The Lack of the Essential LptC Protein in the Trans-Envelope Lipopolysaccharide Transport Machine Is Circumvented by Suppressor Mutations in LptF, an Inner Membrane Component of the Escherichia coli Transporter DOI PubMedBenedet M, Falchi FA, Puccio S, Di Benedetto C, Peano C, Polissi A, Dehò G.
PLoS One. 2016 Aug 16;11(8):e0161354. doi: 10.1371/journal.pone.0161354. eCollection 2016 PMID:27529623
Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin DOI PubMed
Croci R, Bottaro E, Chan KW, Watanabe S, Pezzullo M, Mastrangelo E, Nastruzzi C.
Int J Biomater. 2016;2016:8043983. doi: 10.1155/2016/8043983. Epub 2016 May 8.
Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking ?(1,3)-glucan remodeling DOI PubMed
Degani G, Ragni E, Botias P, Ravasio D, Calderon J, Pianezzola E, Rodriguez-Peña JM, Vanoni MA, Arroyo J, Fonzi WA, Popolo L.
BMC Genomics. 2016 Jul 2;17:482. doi: 10.1186/s12864-016-2853-5 PMID:27411447
ABA-dependent control of GIGANTEA signalling enables drought escape via up-regulation of FLOWERING LOCUS T in Arabidopsis thaliana DOI PubMed
Riboni M, Robustelli Test A, Galbiati M, Tonelli C, Conti L.
J Exp Bot. 2016 Dec;67(22):6309-6322. Epub 2016 Oct 12.
A novel role for STOMATAL CARPENTER 1 in stomata patterning DOI PubMed
Castorina G, Fox S, Tonelli C, Galbiati M, Conti L.
BMC Plant Biol. 2016 Aug 2;16(1):172. doi: 10.1186/s12870-016-0851-z
Whole-gene CFTR sequencing combined with digital RT-PCR improves genetic diagnosis of cystic fibrosis. DOI PubMed
Straniero L, Soldà G, Costantino L, Seia M, Melotti P, Colombo C, Asselta R, Duga S.
J Hum Genet. 2016 Dec;61(12):977-984. doi: 10.1038/jhg.2016.101.
PGR5-PGRL1-Dependent Cyclic Electron Transport Modulates Linear Electron Transport Rate in Arabidopsis thaliana. DOI PubMed
Suorsa M, Rossi F, Tadini L, Labs M, Colombo M, Jahns P, Kater MM, Leister D, Finazzi G, Aro EM, Barbato R, Pesaresi P.
Mol Plant. 2016 Feb 1;9(2):271-288. doi: 10.1016/j.molp.2015.12.001. Epub 2015 Dec 11PMID: 26687812
Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant. DOI PubMed
Bonì F, Milani M, Porcari R, Barbiroli A, Ricagno S, de Rosa M.
Sci Rep. 2016 Sep 16;6:33463
Seed abscission and fruit dehiscence required for seed dispersal rely on similar genetic networks DOI PubMed AIR
Vicente Balanzà, Irma Roig-Villanova, Maurizio Di Marzo, Simona Masiero and Lucia Colombo
Development
Searching for the in vivo transcriptome blueprint of competent bovine oocytes DOI AIR
V. Bocchi, M.G. Strillacci, A. Zecconi, C. Galli, G. Stadaioli, T.A.L. Brevini, A. Bagnato, F. Gando
REPRODUCTION FERTILITY AND DEVELOPMENT
GUN1, a Jack-Of-All-Trades in Chloroplast Protein Homeostasis and Signaling DOI AIR
M. Colombo, L. Tadini, C. Peracchio, R. Ferrari, P. Pesaresi
FRONTIERS IN PLANT SCIENCE
2015
A covalent homodimer probing early oligomers along amyloid aggregation DOI PubMedHalabelian L, Relini A, Barbiroli A, Penco A, Bolognesi M, Ricagno S.
Sci Rep. 2015 Sep 30;5:14651. doi: 10.1038/srep14651.
An improved expression system for the VC1 ligand binding domain of the receptor for advanced glycation end products in Pichia pastoris DOI PubMed
Degani G, Colzani M, Tettamanzi A, Sorrentino L, Aliverti A, Fritz G, Aldini G, Popolo L.
Protein Expr Purif. 2015 Oct;114:48-57. doi: 10.1016/j.pep.2015.06.012. Epub 2015 Jun 25 PMID:26118699
Catalytic properties of Phr family members of cell wall glucan remodeling enzymes: implications for the adaptation of Candida albicans to ambient pH DOI PubMed
Kováčová K#, Degani G#, Stratilová E, Farkaš V, Popolo L.
FEMS Yeast Res. 2015 Mar;15(2). pii: fou011. doi: 10.1093/femsyr/fou011. Epub 2015 Mar 10 PMID:25757890
The expanding spectrum of PRPS1-associated phenotypes: three novel mutations segregating with X-linked hearing loss and mild peripheral neuropathy. DOI PubMed
Robusto M, Fang M, Asselta R, Castorina P, Previtali SC, Caccia S, Benzoni E, De Cristofaro R, Yu C, Cesarani A, Liu X, Li W, Primignani P, Ambrosetti U, Xu X, Duga S, Soldà G.
Eur J Hum Genet. 2015 Jun;23(6):766-73. doi: 10.1038/ejhg.2014.168.
Two novel splicing mutations in the SLC45A2 gene cause Oculocutaneous Albinism Type IV by unmasking cryptic splice sites DOI PubMed
Straniero L, Rimoldi V, Soldà G, Mauri L, Manfredini E, Andreucci E, Bargiacchi S, Penco S, Gesu GP, Del Longo A, Piozzi E, Asselta R, Primignani P.
J Hum Genet. 2015 Sep;60(9):467-71. doi: 10.1038/jhg.2015.56.
Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD(+)/H Binding to Mitochondrial Apoptosis-Inducing Factor. DOI PubMed
Sorrentino L, Calogero AM, Pandini V, Vanoni MA, Sevrioukova IF, Aliverti A.
Biochemistry. 2015 Dec 1;54(47):6996-7009. doi: 10.1021/acs.biochem.5b00898. Epub 2015 Nov 16.
Effects of sublethal doses of silver nanoparticles on Bacillus subtilis planktonic and sessile cells DOI PubMed
Gambino M, Marzano V, Villa F, Vitali A, Vannini C, Landini P, Cappitelli F.
J Appl Microbiol. 2015 May;118(5):1103-15. doi: 10.1111/jam.12779. Epub 2015 Mar 17
Engineering a Ca++-sensitive (bio)sensor from the pore-module of a potassium channel DOI PubMed
DiFrancesco ML, Gazzarrini S, Arrigoni C, Romani G, Thiel G, Moroni A.
Sensors (Basel). 2015 Feb 27;15(3):4913-24. doi: 10.3390/s150304913.
Structure-based design of a B cell antigen from B. pseudomallei DOI PubMed
Gaudesi D, Peri C, Quilici G, Gori A, Ferrer-Navarro M, Conchillo-Solé O, Thomas R, Nithichanon A, Lertmemongkolchai G, Titball R, Daura X, Colombo G, Musco G.
ACS Chem Biol. 2015 Mar 20;10(3):803-12. doi: 10.1021/cb500831y. Epub 2014 Dec 22.
Prediction of Antigenic B and T Cell Epitopes via Energy Decomposition Analysis: Description of the Web-Based Prediction Tool BEPPE DOI PubMed
Peri C, Solé OC, Corrada D, Gori A, Daura X, Colombo G
Methods Mol Biol. 2015;1348:13-22. doi: 10.1007/978-1-4939-2999-3_3
A whole-cell assay for specific inhibitors of translation initiation in bacteria DOI AIR
M. Raneri, B. Sciandrone, F. Briani
JOURNAL OF BIOMOLECULAR SCREENING
Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation DOI AIR
T. Touvier, C. De Palma, E. Rigamonti, A. Scagliola, E. Incerti, L. Mazelin, J. Thomas, M. D'Antonio
CELL DEATH & DISEASE
2014
Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic β2-microglobulin DOI PubMedHalabelian L, Ricagno S, Giorgetti S, Santambrogio C, Barbiroli A, Pellegrino S, Achour A, Grandori R, Marchese L, Raimondi S, Mangione PP, Esposito G, Al-Shawi R, Simons JP, Speck I, Stoppini M, Bolognesi M, Bellotti V.
J Biol Chem. 2014 Feb 7;289(6):3318-27. doi: 10.1074/jbc.M113.524157. Epub 2013 Dec 13.
A shotgun antisense approach to the identification of novel essential genes in Pseudomonas aeruginosa DOI PubMed
Rusmini R, Vecchietti D, Macchi R, Vidal-Aroca F, Bertoni G.
BMC Microbiol. 2014 Feb 5;14:24. doi: 10.1186/1471-2180-14-24.
Tet-Trap, a genetic approach to the identification of bacterial RNA thermometers: application to Pseudomonas aeruginosa DOI PubMed
Delvillani F, Sciandrone B, Peano C, Petiti L, Berens C, Georgi C, Ferrara S, Bertoni G, Pasini ME, Dehò G, Briani F.
RNA. 2014 Dec;20(12):1963-76. doi: 10.1261/rna.044354.114. Epub 2014 Oct 21 PMID:25336583
PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases DOI PubMed
Croci R, Tarantino D, Milani M, Pezzullo M, Rohayem J, Bolognesi M, Mastrangelo E.
FEBS Lett. 2014 May 2;588(9):1720-5. doi: 10.1016/j.febslet.2014.03.021. Epub 2014 Mar 18.
Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds DOI PubMed
Croci R, Pezzullo M, Tarantino D, Milani M, Tsay SC, Sureshbabu R, Tsai YJ, Mastrangelo E, Rohayem J, Bolognesi M, Hwu JR.
PLoS One. 2014 Mar 12;9(3):e91765. doi: 10.1371/journal.pone.0091765.
Effect of cytosolic pH on inward currents reveals structural characteristics of the proton transport cycle in the influenza A protein M2 in cell-free membrane patches of Xenopus oocytes DOI PubMed
DiFrancesco ML, Hansen UP, Thiel G, Moroni A, Schroeder I.
PLoS One. 2014 Sep 11;9(9):e107406. doi: 10.1371/journal.pone.0107406. eCollection 2014.
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function DOI PubMed
Saponaro A, Pauleta SR, Cantini F, Matzapetakis M, Hammann C, Donadoni C, Hu L, Thiel G, Banci L, Santoro B, Moroni A.
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14577-82. doi: 10.1073/pnas.1410389111. Epub 2014 Sep 2.
Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness DOI PubMed
Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Schroeder I, Simmons K, Aquila M, DiFrancesco D, Bolognesi M, Schwede F, Kashin D, Fishwick CW, Johnson AP, Thiel G, Moroni A.
Nat Chem Biol. 2014 Jun;10(6):457-62. doi: 10.1038/nchembio.1521.
hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3'-UTR and oppositely regulate its expression DOI PubMed
Zuccotti P, Colombrita C, Moncini S, Barbieri A, Lunghi M, Gelfi C, De Palma S, Nicolin A, Ratti A, Venturin M, Riva P.
Biochim Biophys Acta. 2014 Jun;1839(6):506-16. doi: 10.1016/j.bbagrm.2014.04.018. Epub 2014 May 2 PMID:24792867
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