www.unimi.it bioscienze.bio Dipartimento Bioscienze

FotoLavinia Grasso
Email: lavinia.grasso@unimi.it
Cicle: XXXV A.Y. 2019 - 2020
Supervisor: Giulio Pavesi
Title: Accumulation of replication/repair intermediates as a cause for genomic instability: integrated in vivo and in silico studies … read more

External links: ResearchGate ORCID


Curriculum vitae: >>>


PhD Seminars:
Date Title Speakers
17/10/2019 Mechanistic drivers of cancer cell plasticity Lynne-Marie Postovit
12/11/2019 Unveiling RNA Polymerase III (Extra) Transcriptional Complexes with EM Alessandro Vannini
19/11/2019 Role of unusual RNA/DNA structures in health and disease Natalia Gromak
29/11/2019 Molecular mechanisms regulating mitochondrial function and dysfunction in neurological disorders Antonella Scorziello
21/01/2020 Two short stories: nucleosomes protect DNA from damage and restrain cell reprogramming Marco Bianchi
23/01/2020 The role of miR-182 in zebrafish heart development: a TBX5-controlled miRNA in Holt-Oram Syndrome Elena Guzzolino
31/01/2020 Crystallographic enzymology: EMBL beamlines on PETRAIII for high resolution in space and time Thomas R. Schneider
14/02/2020 Unveiling the role of DNA repetitive elements in human genome plasticity Beatrice Bodega
17/02/2020 QX200 Droplet Digital PCR System: workflow and advanced application Marilisa Marinelli
01/04/2020 Decoding the non-coding: the small, the long and the antisense Paolo Gandellini
22/04/2020 Computational structural biology @Unimi: what can we learn from how proteins move Carlo Camilloni
22/04/2020 GLOE-Seq – a new genomic tool to map replication patterns and DNA lesions with nucleotide resolution Helle D. Ulrich
23/04/2020 RSC readies the quiescent genome for rapid hypertranscription Christine Cucinotta
27/04/2020 La percezione pubblica della scienza: i giovani ricercatori di fronte a temi scientifici di forte interesse pubblico, politico e mediatico Multiple Speakers
05/05/2020 Nanopore sequencing 101 James Brayer, Oliver Lucas
28/05/2020 Covid-19: come si insegue e sconfigge un virus Multiple Speakers
02/06/2020 Microbiology with Oxford Nanopore Technologies Sudha Rao, Jacob Ortvig, Dan Fordham
03/06/2020 The transcription factor Nfix requires Rhoa-Rock1 dependent phagocytosis to mediate macrophages skewing during skeletal muscle regeneration Marielle Saclier
01/10/2020 Unintended consequences of replication stress Philippe Pasero
04/11/2020 Defining novel mechanisms in angiogenesis Alessandro Fantin
02/12/2020 Novel roles for Haspin kinase: from cell polarization to cilia and lysosome regulation Roberto Quadri
03/12/2020 Mechanisms of stalled replication fork repair in mammalian cells Ralph Scully
21/01/2021 Unexpected dependencies introduced by sRNA-mediated regulations Matteo Brilli
28/01/2021 How did thalidomide do what it did? Neil Vargesson
28/01/2021 Chromosome damage repair via the BRCA tumor suppressor axis Patrick Sung
24/02/2021 Department of Excellence Workshop Multiple Speakers
25/02/2021 Formation and resolution of replication-associated recombination intermediates Dana Branzei
08/04/2021 Understanding causes and consequences of DNA replication stress in vertebrate organisms Vincenzo Costanzo
30/04/2021 The pioneer transcription factor FOXA1 calibrates the pre-mRNA alternative splicing landscape of human prostate cancer Matteo Cereda
06/05/2021 Uncovering key processes in replication fork remodeling and repair via single-molecule imaging Eli Rothenberg
03/06/2021 Chromatin and chromosome dynamics at DNA Double Strand Breaks Gaelle Legube
03/06/2021 How molecular combing technology is transforming genomic research through visualizing DNA at single-molecule level Mark Lynch
08/07/2021 Regulation of DSB repair pathway choice by BRCA1, 53BP1 and friends Ross Chapman
19/08/2021 DNA repair mechanisms in heterochromatin Irene Chiolo
09/09/2021 Mutations arising during repair of a broken chromosome Jim Haber
16/09/2021 A tale of two genomes: DNA repair in the mitochondria and the nucleus Agnel Sfeir
03/11/2021 Use of an old drug for new diseases - repositioning of Thalidomide for COVID-19 and Kawasaki disease Luisa Guerrini
02/02/2022 Transcription and dynamics of transposable elements keeps on fire the genome of human T lymphocytes Beatrice Bodega
27/05/2022 Primordial maintenance of genetic information: the Virtual Circular Genome mode Marco Todisco
20/10/2022 Accurate modeling DNA deformability and its role in protein binding Martin Zacharias
28/10/2022 Long noncoding RNA functions in healthy and diseased cells Rory Johnson
04/11/2022 Ligands stimulating antitumour immunity as the next G-quadruplex challenge Giovanni Capranico
17/11/2022 12th Magni lecture "Genetic instability: from RNA to replication stress" Andrés Aguilera
27/01/2023 Twisting the boundaries: Role of DNA topoisomerases at the nuclear lamina Stefano Manzo
12/05/2023 Illuminating radial genome organization in the nucleus Magda Bienko

PhD Courses:
Starting Date Ending Date Title Place
21/11/2019 22/11/2019 Introduzione all'esplorazione dati in R Università degli Studi di Milano
03/02/2020 07/02/2020 Molecular and Cellular Biology: Methods and Communication of Results Università degli Studi di Milano
23/06/2020 30/06/2020 Introduction to transcriptomic analysis Università degli studi di Milano
21/09/2020 21/09/2020 New advances in basic and applied virology Università degli studi di Milano
13/01/2021 26/01/2021 Biostatistics for molecular and cellular biology Università degli studi di Milano
13/09/2021 16/09/2021 Modern Imaging Techniques in Biology Università degli studi di Milano

Conferences / Workshops:
Starting Date Ending Date Title Place
27/03/2022 01/04/2022 11th Quinquennial Conference on Responses to DNA damage: from molecule to disease Egmond aan Zee, The Netherlands
31/03/2023 31/03/2023 Single-molecule Sequencing Technologies & Applications Human Technopole, Milan
26/06/2023 28/06/2023 18th SIBBM seminars - Frontiers in Molecular Biology Bari

Publications:

 One, No One, and One Hundred Thousand: The Many Forms of Ribonucleotides in DNA
Giulia Maria Nava, Lavinia Grasso, Sarah Sertic, Achille Pellicioli, Marco Muzi Falconi, and Federico Lazzaro
International Journal of Molecular Sciences

 Ethanol exposure increases mutation rate through error-prone polymerases
Karin Voordeckers, Camilla Colding, Lavinia Grasso, et al.
Nature Communications

 RNase H activities counteract a toxic effect of Polymerase in cells replicating with depleted dNTP
A. Meroni, G.M. Nava, E. Bianco, L. Grasso, E. Galati, M.C. Bosio, D. Dalmastro, M. Muzi Falconi, F.
NUCLEIC ACIDS RESEARCH



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