www.unimi.it bioscienze.bio Dipartimento Bioscienze

FotoLuca Broggini
Email: luca.broggini@unimi.it
Cicle: XXXIII A.Y. 2017 - 2018
Supervisor: Stefano Ricagno
Titol: Structural and biophysical studies on Neuroserpin neurotoxic polymers … read more

Conferences / Workshops:
Starting Date Ending Date Title Place
27/01/2019 30/01/2019 NMR: a tool for biology Insitut Pasteur, Paris, France
08/07/2019 13/07/2019 EMBO course: Integrative structural and cellular biology Insitut Pasteur, Paris, France
14/10/2019 20/10/2019 EMBO course: Structural and biophysical methods for biological macromolecules in solution Santiago de Chile, Chile

External links: Scopus Linkedin


 Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State
Visconti L., Malagrinò F., Broggini L., De Luca CMG., Moda F., Gianni S., Ricagno S., Toto A.
International Journal of Molecular Sciences

 Biochemical and biophysical comparison of human and mouse beta‐2 microglobulin reveals the molecular determinants of low amyloid propensity
Achour A., Broggini L., Han X., Sun R., Santambrogio C., Buratto J., Visentin C., Barbiroli A., De Luca C., Sormanni P., Moda F., De Simone A., Sandalova T., Grandori R., Camilloni C., Ricagno S.
The FEBS journal

 Glycosylation Tunes Neuroserpin Physiological and Pathological Properties
Visentin C., Broggini L., Sala B., Russo R., Barbiroli A., Santambrogio C., Nonnis S., Dubnovitsky A., Bolognesi M., Miranda E., Achour A., Ricagno S.
International Journal of Molecular Sciences

 Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors
Visentin C., Musso L., Broggini L., Bonato F., Russo R., Moriconi C., Bolognesi M., Miranda E., Dellavalle S., Passarella D., Ricagno S.

Curriculum vitae: >>>

Immagine linee di ricerca
Native neuroserpin mechanism of action

Native to cleaved state transition. Upon cleavage of the scissile bond, the reactive center loop is inserted within β-strand A forming a stable and inactive cleaved state.



  Via Giovanni Celoria 26 – 20133 Milano
  Sito istituzionale del dipartimento
  Come raggiungere il Dipartimento di Bioscienze

Segreterie - Infostudenti
  Segreterie - Infostudenti

© Copyright 2017 - 2021