www.unimi.it bioscienze.bio Dipartimento Bioscienze

FotoDavide Scalzo
Email: davide.scalzo@unimi.it
Cicle: XL A.Y. 2024 - 2025
Supervisor: Elena Cattaneo
Title: Development of a stem cell platform for studying cag somatic instability in huntington's disease through single-cell dna sequencing and transcriptional profiling of brain organoids and treated hd animal brains … read more

PhD Seminars:
Date Title Speakers
08/11/2024 AA amyloidosis: a severe disease but also a model for studying amyloid-related questions Prof. Gunilla Westermark
27/11/2024 40 years of research on cell therapy for Parkinson's disease Dr. Anders Bjorklund
27/11/2024 First and second-generation strategies in developing a cell-based therapy for Parkinson's disease Dr. Lorenz Studer
17/01/2025 Analyses of conduction and selectivity in potassium channels by Markov Models based on Molecular Dynamics simulations Prof. Simone Furini
24/01/2025 Targeting hyperpolarisation-activated cyclic nucleotide-gated channels in the treatment of neurological disorders Dr. Kevin Cunninghan
31/01/2025 Sialoconjugates as new players in Huntington's disease: insights into molecular mechanisms and potential therapies Dr. Vittorio Maglione
04/03/2025 Exploiting LIBRA-seq technology to discover potential therapeutic antibodies against Klebsiella pneumoniae multidrug resistance Dr. Elisa Pesce and Dr. Andrea Gobbini

PhD Courses:
Starting Date Ending Date Title Place
13/01/2025 03/02/2025 Biostatistics for Molecular and Cellular Biology Università degli Studi di Milano
10/02/2025 24/02/2025 Methods and Comunications of Results Università degli Studi di Milano

Conferences / Workshops:
Starting Date Ending Date Title Place
27/11/2024 27/11/2024 Stem cell revolutions for neurodegenerative diseases Milan
04/02/2025 05/02/2025 Advanced Technologies in Single Cell Omics Università degli Studi di Milano, Via Festa del Perdono 7

Publications:

 When repetita no-longer iuvant: somatic instability of the CAG triplet in Huntington’s disease
Elena Cattaneo, Davide Scalzo, Martina Zobel, Raffaele Iennaco, Camilla Maffezzini, Dario Besusso, Simone Maestri
Nucleic Acids Research

 Navigating triplet repeats sequencing: concepts, methodological challenges and perspective for Huntington’s disease
Simone Maestri, Davide Scalzo, Gianluca Damaggio, Martina Zobel, Dario Besusso, Elena Cattaneo
Nucleic Acids Research



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