Davide Scalzo
Email:
davide.scalzo@unimi.it
Cicle:
XL A.Y.
2024 - 2025
Supervisor:
Elena Cattaneo
Title:
Development of a stem cell platform for studying cag somatic instability in huntington's disease through single-cell dna sequencing and transcriptional profiling of brain organoids and treated hd animal brains … read more
PhD Seminars:
| Date |
Title |
Speakers |
| 08/11/2024 |
AA amyloidosis: a severe disease but also a model for studying amyloid-related questions |
Prof. Gunilla Westermark |
| 27/11/2024 |
40 years of research on cell therapy for Parkinson's disease |
Dr. Anders Bjorklund |
| 27/11/2024 |
First and second-generation strategies in developing a cell-based therapy for Parkinson's disease |
Dr. Lorenz Studer |
| 17/01/2025 |
Analyses of conduction and selectivity in potassium channels by Markov Models based on Molecular Dynamics simulations |
Prof. Simone Furini |
| 24/01/2025 |
Targeting hyperpolarisation-activated cyclic nucleotide-gated channels in the treatment of neurological disorders |
Dr. Kevin Cunninghan |
| 31/01/2025 |
Sialoconjugates as new players in Huntington's disease: insights into molecular mechanisms and potential therapies |
Dr. Vittorio Maglione |
| 04/03/2025 |
Exploiting LIBRA-seq technology to discover potential therapeutic antibodies against Klebsiella pneumoniae multidrug resistance |
Dr. Elisa Pesce and Dr. Andrea Gobbini |
| 08/04/2025 |
Studying the lifecycle of pathogenic huntingtin mRNA species through a flexible embryonic stem cell platform |
Dr. Camilla Maffezzini |
| 19/05/2025 |
Deciphering cellular and molecular mechanisms underlying cardiac fibrosis |
Dr. Nuno Camboa |
| 26/05/2025 |
Leveraging the Power of Mendelian Genetics for Drug Development |
Dr. Bruno Reversade |
PhD Courses:
| Starting Date |
Ending Date |
Title |
Place |
| 13/01/2025 |
03/02/2025 |
Biostatistics for Molecular and Cellular Biology |
Università degli Studi di Milano |
| 10/02/2025 |
24/02/2025 |
Methods and Comunications of Results |
Università degli Studi di Milano |
| 16/06/2025 |
20/06/2025 |
Genomics for ecological and evolutionary studies from DNA sequencing to data analysis |
Università degli Studi di Milano |
Conferences / Workshops:
| Starting Date |
Ending Date |
Title |
Place |
| 27/11/2024 |
27/11/2024 |
Stem cell revolutions for neurodegenerative diseases |
Milan |
| 04/02/2025 |
05/02/2025 |
Advanced Technologies in Single Cell Omics |
Università degli Studi di Milano, Via Festa del Perdono 7 |
Publications:
When repetita no-longer iuvant: somatic instability of the CAG triplet in Huntington’s disease Elena Cattaneo, Davide Scalzo, Martina Zobel, Raffaele Iennaco, Camilla Maffezzini, Dario Besusso, Simone Maestri
Nucleic Acids Research
Navigating triplet repeats sequencing: concepts, methodological challenges and perspective for Huntington’s diseaseSimone Maestri, Davide Scalzo, Gianluca Damaggio, Martina Zobel, Dario Besusso, Elena Cattaneo
Nucleic Acids Research
A human CAGinSTEM platform for decoding HTT repeats' somatic instability links CAG interruption to HD pathology in neuronsMartina Zobel, Gianluca Damaggio, Maria Lidia Mignogna, Dario Besusso, Davide Scalzo, Andrea Cossu, Camilla Trovesi, Mariacristina Crosti, Francesco Cortina, Ilaria Campus, Giulio Formenti, Saveria Mazzara, Francesco Gregoretti, Laura Antonelli, Gennaro Oliva, Chiara Zuccato, Vincenza Colonna, Paola Conforti, Matteo Cereda, Riccardo Lorenzo Rossi, Simone Maestri, Andrea Scolz, Raffale Iennaco, Elena Cattaneo
Cell Reports