Melissa Milazzo
Email: melissa.milazzo@unimi.it
Cicle: XXXIX A.Y. 2023 - 2024
Supervisor: Stefano Ricagno
Title: Biochemical and structural characterisation of toxic protein aggregates from cats affected by AA amyloidosis to design future treatments … read more


Curriculum vitae: >>>


PhD Seminars:

Date	Title	Speakers
20/10/2023	Chaperone regulation of the protein condensation and aggregation continuum in ALzheimer's Disease	prof. Claudio Gomes
23/10/2023	Identification of new targets to promote cardiac regeneration and prevent cardiac fibrosis	prof. Paola Cattaneo
03/11/2023	Conformational ensembles of the human intrinsically disordered proteome	prof. Kresten Lindorff-Larsen
10/11/2023	Discovering new genetic determinants of chemotherapy resistance in BRCA- deficient tumors	Dr. Diego Dibitetto
10/11/2023	Workshop "Peptide and protein talks"	Dr. Alessandro Gori, Prof. Paolo Arosio, Dr. Luca Colnaghi, Dr. Anna Barbieri, Prof. Claudia Bello, Prof. Ferdinando Fiumara, Dr. Rosanna Mezzapelle, Dr. C. Chirizzi, Dr. S. Garbujo, Dr. G. Ciulla
01/12/2023	Blocking channels to metastasis: targeting sodium transport in breast cancer	prof. William Brackenbury
19/01/2024	Neuromuscular organoids for studying the human neuromuscular system in vitro	D.ssa Anna Ucriuolo
07/10/2024	13th PhD Workshop	PhD students, XXXVIII cycle
08/11/2024	AA amyloidosis: a severe disease but also a model for studying amyloid-related questions	Gunilla Westermark
24/11/2024	Thermo Scientific Seminar "Bound Together: Mass Spectrometry and Cryo-EM"	Andrea Graziadei, Albert Konijnenberg, Rosa Viner, Francesca Coscia, Carlo Santambrogio, Ulrik Mistarz
25/11/2024	Beyond the ends: the hidden functions and power of telomeric repeats	Prof. Petra Prochàzkovà Schrumpfovà
25/11/2024	Beyond the ends: the hidden functions and power of telomeric repeats	Prof. Petra Procházková Schrumpfová

PhD Courses:

Starting Date	Ending Date	Title	Place
22/11/2023	17/01/2024	Protein structure, prediction and design: how to use AlphaFold and other AI methods for your research	Dipartimento di Bioscienze, Università degli Studi di Milano
08/01/2024	31/01/2024	Biostatistics for molecular and cellular biology	Dipartimento di Bioscienze, Università degli Studi di Milano
26/02/2024	04/03/2024	Molecular and Cellular Biology: Methods and Communication of Results	Dipartimento di Bioscienze, Università degli Studi di Milano
26/02/2024	26/02/2024	Introduzione all'Open Science, part 1	Dipartimento di Bioscienze, Università degli Studi di Milano
26/02/2024	26/02/2024	Open Science: Riviste Predatorie, Preprint e Open Peer Review	Dipartimento di Bioscienze, Università degli Studi di Milano
26/02/2024	26/02/2024	Research Integrity in Practice	Dipartimento di Bioscienze, Università degli Studi di Milano
28/02/2024	28/02/2024	Fondamenti di Academic Writing, part 1	Dipartimento di Bioscienze, Università degli Studi di Milano
28/02/2024	28/02/2024	Language Coaching: Interpersonal Skills, Presentation Skills, part 1	Dipartimento di Bioscienze, Università degli Studi di Milano
29/02/2024	29/02/2024	Fondamenti di Academic Writing, part 2	Dipartimento di Bioscienze, Università degli Studi di Milano
29/02/2024	29/02/2024	Language Coaching: Interpersonal Skills, Presentation Skills, part 2	Dipartimento di Bioscienze, Università degli Studi di Milano
01/03/2024	01/03/2024	Caso studio: La Protezione dei dati nella ricerca	Dipartimento di Bioscienze, Università degli Studi di Milano
08/10/2024	18/10/2024	Hands-on introduction to machine learning and deep learning for biology	Dipartimento di Bioscienze, Università degli Studi di Milano
02/12/2024	06/12/2024	Membrane protein structural biology: history, methods, and some results	Dipartimento di Bioscienze, Università degli Studi di Milano

Conferences / Workshops:

Starting Date	Ending Date	Title	Place
05/02/2024	08/02/2024	The 8th Workshop Physics of Biomolecules: Structure, Dynamics and Function	Bressanone
29/02/2024	29/02/2024	Meet the Biochemist in the Secret Garden	Botanic Garden, Università degli Studi di Milano
26/05/2024	30/05/2024	The 2024 International Symposium on Amyloidosis	Mayo Clinic, Rochester, Minnesota
29/06/2024	30/07/2024	48th Congress of the Federation of European Biochemical Societies	Milan
18/07/2024	19/07/2024	LMB GSA Symposium	MRC Laboratory of Molecular Biology, Cambridge
11/09/2024	13/09/2024	The Leuven Protein Aggregation Meeting	Leuven
12/02/2025	14/02/2025	Protein misfolding and aggregation in disease	Mantova
17/02/2025	19/02/2025	Ph.D. Course in Molecular and Cellular Biology: the RETREAT 2025	Bertinoro

Posters:

Date	Title	Place	File
29/06/2024	Caratterizzazione strutturale in microscopia crioelettronica di fibrille di un gatto affetto da Amiloidosi AA	Botanic Garden, Università degli Studi di Milano
30/06/2024	Structural characterisation of pathological protein aggregates in a cat affected by systemic AA amyloidosis	Milan
11/09/2024	Multiorgan cryo-EM structural analysis of feline AA amyloid aggregates	Leuven
13/02/2025	Structural analysis of pathological AA amyloids from feline heart and liver shows polymorphic fibrils	Mantova

Publications:

 AA amyloidosis in vertebrates: epidemiology, pathology and molecular aspects
Valentina Moccia, Claudia Maria Tucciarone, Silvia Garutti, Melissa Milazzo, Filippo Ferri, Carlo Palizzotto, Maria Mazza, Marco Basset, Eric Zini, Stefano Ricagno, Silvia Ferro
Amyloid, The Journal of Protein Folding Disorders

 Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis
Tim Schulte, Antonio Chaves-Sanjuan, Valentina Speranzini, Kevin Sicking, Melissa Milazzo, Giulia Mazzini, Paola Rognoni, Serena Caminito, Paolo Milani, Chiara Marabelli, Alessandro Corbelli, Luisa Diomede, Fabio Fiordaliso, Luigi Anastasia, Carlo Pappone, Giampaolo Merlini, Martino Bolognesi, Mario Nuvolone, Rubén Fernández-Busnadiego, Giovanni Palladini, Stefano Ricagno
Nature Communications