www.unimi.it bioscienze.bio Dipartimento Bioscienze

FotoGiulia Rizzi
Email: giulia.rizzi2@unimi.it
Cicle: XXXVIII A.Y. 2022 - 2023
Supervisor: Stefano Ricagno
Title: The lysosomal amyloid aggregation of β2-microglobulin promotes Multiple myeloma progression: a molecular focus on this pro-cancer mechanism … read more

PhD Seminars:
Date Title Speakers
28/10/2022 Accurate modeling DNA deformability and its role in protein binding Prof. Martin Zacharias
04/11/2022 Harnessing the Power of Computer Graphics for Structural Biology with Blender & Molecular Nodes Dr. Brady Johnston
24/11/2022 Transcriptional control of myeloid cell identity and activation Prof. Renato Ostuni
25/11/2022 Study of the effects of using different water-saving strategies on plant growth, yield and photosynthesis in different crops grown under Mediterranean climate conditions in northeastern Morocco Prof. Kamal Aberkani
19/12/2022 Evolution of visual circuits and disease modeling in zebrafish Dr. Filippo Del Bene
27/01/2023 Twisting the boundaries: Role of DNA topoisomerases at the nuclear lamina Dr. Stefano Manzo
05/04/2023 Hematopoietic stem/progenitor cell-gene therapy in inborns error of metabolism Prof. Maria Ester Bernardo
09/05/2023 Causes and consequences of DNA replication stress in cancer and stem cells Prof. Vincenzo Costanzo
15/05/2023 Understanding biomolecular behaviour with mass photometry Dr. Perla Vega Dominguez
23/06/2023 The cold side of connectivity. A journey in the Southern Ocean with Antarctic fish. Prof.ssa Chiara Papetti
26/06/2023 The Bigfoot cell sorter - Performances and Flexibility & Better flow data with cell imaging – Discover the Attune CytPix Dr. Guerric Epron and Dr. Claudio Comunian
30/06/2023 Fighting fungal disease in eggplant: from allied source of resistance to the gene Dott.ssa Laura Toppino
04/07/2023 Molecular and functional heterogeneity in dorsal and ventral oligodendrocyte progenitor cells of the mouse forebrain in response to DNA damage Prof. Enrica Boda
14/07/2023 Bacterial exoskeletons and where to find them: the Bacillus anthracis case Dott.ssa Antonella Fioravanti
18/07/2023 Uno sguardo ad ampio spettro sul futuro della citometria a flusso Dr. Enrico Ghersi
12/09/2023 Two HCN4 channels in zebrafish: biophysical properties and physiological roles Dr. Koichi Nakajo
12/09/2023 Ultrasound sensitive ion channels an sonogenetics for neural stimulation Prof. Jianmin Cui
12/09/2023 Structural determinants of the Ivabradine block of pacemaker HCN channels Dr. Andrea Saponaro
12/09/2023 Quaternary structure independent folding of voltage-gated ion channel pore domain subunits Dr.ssa Cristina Arrigoni
12/09/2023 Potassium channel activators Prof. Fredrik Elinder
20/10/2023 Chaperone regulation of the protein condensation and aggregation continuum in Alzheimer's disease Prof Claudio Gomes
23/10/2023 Identification of new targets to promote cardiac regeneration and prevent cardiac fibrosis Dr.ssa Paola Cattaneo
03/11/2023 Conformational ensembles of the human intrinsically disordered proteome Prof. Kresten Lindorff-Larsen
01/12/2023 Blocking channels to metastasis: targeting sodium transport in breast cancer Prof. William Brackenbury
02/02/2024 What the structures of amyloids teach us about amyloid pathology Prof Joost Schymkowitz
01/03/2024 Ex vivo gene therapy for DMD: steps towards efficacy Prof. Giulio Cossu
04/04/2024 Cation transport system in bacteria and plant cells Prof. Nobuyuki Uozumi
10/04/2024 New Unexpected Photoreceptors with potential Optogenetic Applications Prof. Peter Hegemann
07/05/2024 Presentation of Massphotometry Dilber Irmak, PhD
12/07/2024 Role of forces in membrane dynamics and liver tissue morphogenesis. Prof. Marino Zerial
23/07/2024 Hacking the polyubiquitin code to control ion channel expression for therapy Prof. Henry Colecraft
10/09/2024 Molecular Simulations for Molecular Design Prof. Giorgio Colombo
10/10/2024 Molecular and cellular mechanism of late endosomal autophagy - dependent secretion - importance in Parkinson's disease and glioma Prof. Thierry Galli
16/10/2024 GlycoSHIELD an integrated approach towards structural glycobiology Prof. Shang-Te Danny Hsu
04/11/2024 Mitochondria in Health and Disease: Bridging Molecular Sciences and Therapeutic Breakthroughs Prof. Carlo Viscomi
08/11/2024 AA amyloidosis: a severe disease but also a model for studying amyloid-related questions Prof. Gunilla Westermark

PhD Courses:
Starting Date Ending Date Title Place
09/01/2023 31/01/2023 Biostatistics for Molecular and Cellular Biology Università degli Studi di Milano
07/03/2023 08/03/2023 Introduzione all'Open Science Online
03/04/2023 04/04/2023 Open Science: riviste predatorie, pre-print e open review Online
17/05/2023 18/05/2023 Open Science: Dati fair Online
20/06/2023 19/07/2023 Comunicazione e nuovi media Celoria 208 e online
17/07/2023 18/07/2023 Fondamenti di academic writing Online
13/09/2023 18/09/2023 Immunology INGM
30/10/2023 30/10/2023 «Formazione Gas Tecnici – Understanding Gases 2023» Conoscere i Gas, Gas Criogenici e rischi connessi. Department of Biosciences, University of Milan
16/02/2024 16/02/2024 Behind the scene of a peer reviewed journal - Parte 1 Online
20/02/2024 20/02/2024 La Proprietà Intellettuale e la tutela brevettuale Online
20/02/2024 20/02/2024 The purpose of a Phd in the knowledge economy Online
22/02/2024 26/06/2024 Preparazione di un piano di disseminazione per un progetto di ricerca Aula 208 e online
23/02/2024 23/02/2024 Exploitation by means of business creation: spin-off and enterpreneurship from an academic point of view Online
23/02/2024 26/02/2024 La valutazione della Sostenibilità integrate per la global health V3 e online
23/02/2024 23/02/2024 Teaching and learning I Online
26/02/2024 04/03/2024 Methods and communication of results Department of Biosciences, University of Milan

Conferences / Workshops:
Starting Date Ending Date Title Place
22/09/2023 22/09/2023 Young Biochemists in Lombardy Università degli Studi di Brescia
05/02/2024 08/02/2024 8th Workshop on Physics of Biomolecules Bressanone
23/05/2024 26/05/2024 COMy Congress 2024 - Controverisies in Multiple Myeloma Pullman Montparnasse, Parigi
28/05/2024 30/05/2024 PhD Meeting 2024 Istituto di Ricerche Farmacologiche Mario Negri
29/06/2024 03/07/2024 48th FEBS Congress MiCo, Milano
14/11/2024 14/11/2024 Bound together: Mass Spectrometry and Cryo-EM Cascina Triulza MIND

Posters:
Date Title Place File
22/09/2023 Novel affinity molecules as target to prevent beta2-microglobulin aggregation Young Biochemists in Lombardy, Università degli Studi di Brescia
23/05/2024 Beta2-microglobulin stability is a crucial factor in the progression of multiple myeloma COMy Congress 2024, Parigi Poster PDF
29/05/2024 Beta2-microglobulin stability is a crucial factor in the progression of multiple myeloma PhD Meeting 2024, Istituto di Ricerche Farmacologiche Mario Negri
29/06/2024 Affibodies as valuable tool to counteract beta2-microglobulin aggregation 48th FEBS Congress, Milano Poster PDF

Abroad experiences:
Starting Date Ending Date Project Institution Supervisor
03/02/2023 18/06/2023 The lysosomal amyloid aggregation of β2-microglobulin promotes Multiple myeloma progression: a molecular focus on this pro-cancer mechanism University Hospital of Erlangen, Germany Heiko Bruns

Publications:

 Apis mellifera RidA, a novel member of the canonical YigF/YER057c/UK114 imine deiminase superfamily of enzymes pre-empting metabolic damage
Cristina Visentin, Giulia Rizzi, Genny Degani, Stefania Digiovanni, Giovanni Robecchi, Alberto Barbiroli, Laura Popolo, Maria Antonietta Vanoni, Stefano Ricagno
Biochemical and Biophysical Research Communications

 Site-directed mutagenesis reveals the interplay between stability, structure and enzymatic activity in RidA from Capra hircus
Giulia Rizzi, Stefania Digiovanni, Genny Degani, Alberto Barbiroli, Flavio Di Pisa, Laura Popolo, Cristina Visentin, Maria Antonietta Vanoni, Stefano Ricagno
Protein Science



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