www.unimi.it bioscienze.bio Dipartimento Bioscienze

FotoRaffaele Epis
Email: raffaele.epis@unimi.it
Phone laboratory: 02 503 14741
Cicle: XXXVIII A.Y. 2022 - 2023
Supervisor: Graziella Messina
Title: Identification of novel compounds to modulate Nfix in muscular dystrophy and Nfix-related diseases … read more


Curriculum vitae: >>>


PhD Seminars:
Date Title Speakers
28/03/2023 PINning down the role of prolyl isomerization in cancer and neurodegeneration. Giannino Del Sal
23/10/2023 Identification of new targets to promote cardiac regeneration and prevent cardiac fibrosis Paola Cattaneo
19/01/2024 Neuromuscular organoids for studying the human neuromuscular system in vitro Anna Urciuolo
16/02/2024 Engineering human skeletal muscle for advanced modelling of neuromuscular diseases and therapeutics Saverio Tedesco
01/03/2024 Ex vivo gene therapy for DMD: steps towards efficacy Giulio Cossu
13/03/2024 From myogenesis to muscle wasting: uncovering new players and therapeutic approaches (Giorgia Careccia) Giorgia Careccia
11/10/2024 In-depth characterization of CFTR variants for personalized medicine approaches in cystic fibrosis Nicoletta Pedemonte
04/11/2024 Mitochondria in Health and Disease: Bridging Molecular Sciences and Therapeutic Breakthroughs Carlo Viscomi
06/12/2024 Structural basis of lipopolysaccharide biosynthesis and modification Filippo Mancia
09/12/2024 Webinar on National Legislation and Ethics IZS dell'Abruzzo e del Molise "G. Caporale"
11/12/2024 The year in cancer cachexia - Cancer Cachexia Society Seminar Alessandro Laviano
09/01/2025 Decoding the regulatory interplay of RNA-binding proteins and cis-elements in cancer Erik Dassi
15/01/2025 The FGF21-IGFBP1 axis drives cachexia and musculoskeletal deficits in colorectal cancer Andrea Bonetto
21/03/2025 Recent Progress in IPS Cell Research and Application Shinya Yamanaka

PhD Courses:
Starting Date Ending Date Title Place
01/09/2022 01/09/2022 BIOLOGIA E GESTIONE DEGLI ANIMALI DA LABORATORIO, MODULI 3.1, 4, 5, 6.1, 7. DM 5 AGOSTO 2021 RODITORI E LAGOMORFI FAD IZSLER
08/11/2022 10/11/2022 GENOMICS FOR ECOLOGICAL AND EVOLUTIONARY STUDIES: FROM DNA SEQUENCING TO DATA ANALYSIS Università degli Studi di Milano
09/01/2023 31/01/2023 BIOSTATISTICS FOR MOLECULAR AND CELLULAR BIOLOGY Università degli Studi di Milano
13/02/2023 20/02/2023 MOLECULAR AND CELLULAR BIOLOGY: METHODS AND COMUNICATION OF RESULTS Università degli Studi di Milano
14/02/2023 14/02/2023 LEGISLAZIONE NAZIONALE ED ETICA LIVELLO 1, MODULI 1 E 2, DM 5 AGOSTO 2021 - 1^ Edizione FAD IZSLER
16/03/2023 16/03/2023 Percorso formativo per funzione A Moduli 3.2 Biologia di Base - 6.2 Eutanasia - 8 Procedure minimamente invasive senza anestesia Specie topo Stabilimento Utilizzatore di Charles River Italia
23/03/2023 30/03/2023 2D, 3D AND 4D IPSC-DERIVED CELLULAR MODELS TO STUDY NEUROMUSCULAR DISEASES Università degli Studi di Milano
15/10/2023 15/10/2023 high training course in Advanced Myology Update Assisi
05/07/2024 08/07/2024 Disease modeling in molecular biomedicine: focus on excitable systems University of Milan

Conferences / Workshops:
Starting Date Ending Date Title Place
11/06/2023 16/06/2023 Myogenesis Gordon Research Conference 2023: Intrinsic and Extrinsic Control of Myogenesis Under Physiological and Pathological Conditions Barga (LU)
12/10/2023 15/10/2023 IIM-Myology Meeting 2023 Assisi
12/10/2024 17/10/2024 EMBO meeting “ Skeletal Muscle Development, Metabolism & Repair during Homeostasis and Disease” Catania

Posters:
Date Title Place File
13/06/2023 Testing of Fluorinated compounds to modulate Nfix in muscular dystrophy Barga (LU)
12/10/2023 Screening of fluorinated compounds to inhibit Nfix in muscular dystrophy Assisi

Abroad experiences:
Starting Date Ending Date Project Institution Supervisor
03/10/2024 04/10/2024 IInd year PhD Progress Report The Francis Crick Institute Francesco Saverio Tedesco

Publications:

 MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet
Giuseppe Angelini, Emanuele Capra, Francesca Rossi, Giada Mura, Marielle Saclier, Valentina Taglietti, Gabriele Rovetta, Raffaele Epis, Giorgia Careccia, Chiara Bonfanti, Graziella Messina
iScience



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