GENOME INSTABILITY AND HUMAN PATHOLOGIES
Genomes are constantly exposed to damage. Failure to repair DNA lesions leads to mutations, which can contribute to ageing and cancer. The main focus of the lab is to characterize DNA repair and cell cycle control mechanisms to understand how defects in these processes contribute to aging, cancer and other genetic syndromes.
Marco Muzi FalconiFull Professor in Molecular Biology
Email: marco.muzifalconi@unimi.it
Thesis available: >>>
External links: ORCID
Main topics of the group:
- Cell cycle control
- DNA damage repair and checkpoint
- Ubiquitin ligases and genome stability
- RNase H and Aicardì Goutiéres Syndrome
Federico LazzaroAssociate Professor in Molecular Biology
Email: federico.lazzaro@unimi.it
Address: IV floor / tower A
Thesis available: >>>
External links: ResearchGate Scopus ORCID
Main topics of the group:
- Cell cycle control
- DNA damage repair and checkpoint
- Ubiquitin ligases and genome stability
- RNase H and Aicardì Goutiéres Syndrome
Achille PellicioliAssociate Professor in Molecular Biology
Email: achille.pellicioli@unimi.it
Phones: +39 02 503 15003
Address: IV floor / tower A
Thesis available: >>>
External links: Scopus ORCID
Keywords: DNA damage and repair, checkpoint, genome instability
Main topics of the group:
- Double strand break response: from basic mechanisms to pathology
- Fanconi anemia pathway and targeted anti-cancer therapy
- Polo kinases and genome instability
Federica MariniAssistant Professor in Molecular Biology
Email: federica.marini@unimi.it
Phones: +39 02 503 15033
Address: IV floor/ tower A
Thesis available: >>>
External links: Scopus ORCID
Main topics of the group:
- Double strand break response: from basic mechanisms to pathology
- Fanconi anemia pathway and targeted anti-cancer therapy
- Polo kinases and genome instability