HUMAN MOLECULAR GENETICS
We study the trimeric transcription factor NF-Y, which has similar structure to histones. We characterize structure/function features and the architecture of regulated genomic regions in relation to epigenetic markers, expression levels, and to the partner transcription factors. Finally, we study its different isoforms involved in pluripotency and cell differentiation.
Website: http://www.mantorlab.unimi.it/mantorlab/sito/sito/Home.html
Roberto MantovaniFull Professor in Genetics
Email: mantor@unimi.it
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Thesis available: >>>
Main topics of the group: - We use genomic and molecular genetic approaches to investigate promoters and enhancers, and the stemness pathways controlled by NF-Y.
Nerina GnesuttaAssociate Professor in Biochemistry
Email: nerina.gnesutta@unimi.it
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Thesis available: >>>
Main topics of the group: - We investigate the structure/function properties of NF-Y and interactions with partner transcription factors with structural and cellular biochemistry approaches
Diletta DolfiniAssistant Professor in Genetics
Email: diletta.dolfini@unimi.it
Thesis available: Ask the teacher
Main topics of the group: Through molecular and genome-wide approaches we investigate regulation of gene expression in human and mouse cells.
Paolo GandelliniAssistant Professor in General Pathology
Email: paolo.gandellini@unimi.it
Address: 7 Floor Tower C
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External links: ResearcherID Scopus ORCID
Keywords: non-coding RNA, human cancer
Main topics of the group: Identification and functional dissection of non-coding RNAs (microRNAs and long non-coding RNAs) in human cancer