www.unimi.it bioscienze.bio Dipartimento Bioscienze

PhD Course in Molecular and Cellular Biology

Research Project Summary XXXV CYCLE – A.Y. 2019-2020


Project leader: Alessandro Aliverti
From protein structure to novel therapeutics against rare genetic diseases … read more

Project leader: Stefano Biffo
Immunoregulation in the tumor microenvironment … read more

Project leader: Aureliano Bombarely
Characterization of the Genetic Basis of the Pawpaw (Asimina triloba) Domestication … read more

Project leader: Maria Cristina Bonza
Characterisation of MIZ1-ECA1 interaction to shed light on the mechanisms underlying long-distance Ca2+ signalling in plants … read more

Project leader: Federica Briani
Exploiting Escherichia coli to understand the molecular defects of disease-linked polynucleotide phosphorylase (hPNPase) variants  … read more

Project leader: Matteo Brilli
Integrating pathogen genomes and health big data for challenging health-associated infections … read more

Project leader: Carlo Camilloni
Molecular modelling of biomolecular self-assembly processes … read more

Project leader: Graziella Cappelletti
Microtubule dysfunction and neurodegeneration: dissecting the interplay of α-synuclein with tubulin in models of Parkinson's disease … read more

Project leader: Marco Cassano
In vivo modelling of liver cancer to resolve the chromatin dependencies of intestinal dysbiosis … read more

Project leader: Elena Cattaneo
Huntington's Disease: biological and molecular aspects in neurons and glia derived from pluripotent stem cells … read more

Project leader: Lucio Conti
Integration of drought and phyto-hormonal signals at the shoot apical meristem of plants … read more

Project leader: Alex Costa
Harnessing the new emerging imaging technologies to uncover the role of Ca2+ signaling in plant nutrient homeostasis … read more

Project leader: Luca Del Giacco
Smpx-deficient zebrafish: a tool for studying human hearing loss … read more

Project leader: Diletta Dolfini
Study of NF-Y expression across TCGA cancer datasets … read more

Project leader: Alessandro Fantin
Defining the molecular and cellular mechanisms by which tissue macrophages promote angiogenesis in neovascular diseases  … read more

Project leader: Fabio Fornara
Uncoupling flowering from internode elongation during the floral transition of rice … read more

Project leader: Paolo Gandellini
Dissecting The Role Of Nfy “Mirnome” In Human Cancer … read more

Project leader: Martin Kater
Functional Analysis of Genes Controlling Inflorescence Architecture in Arabidopsis and Rice … read more

Project leader: Paolo Landini
Role of c-di-GMP and other nucleotide-derived signal molecules in Crohn’s disease-associated host-bacteria interaction … read more

Project leader: Roberto Mantovani
Transcription factor NF-Y partnerships in the regulation of ER-stress response genes … read more

Project leader: Michele Mazzanti
Study of the antiproliferative effect of metformin combined to transcranial stimulation in glioblastoma cellular and animal models … read more

Project leader: Graziella Messina
Development of genetic and pharmacological approaches to cure Muscular Dystrophies … read more

Project leader: Anna Moroni
Engineering of synthetic protein tools for optogenetics … read more

Project leader: Marco Nardini
Biophysical and structural (NMR and crystallography) characterization of the transcription factor Nf1x involved in muscular dystrophy … read more

Project leader: Moira Paroni
Unveiling the AIEC-antigens and gut-microbiota species involved in modulation of pathogenic Th1/17 cells differentiation and activation in Crohn’s disease  … read more

Project leader: Giulio Pavesi
Accumulation of replication/repair intermediates as a cause for genomic instability: integrated in vivo and in silico studies … read more

Project leader: Paolo Pesaresi
SOUP: Signaling the Organelle Unfolded Protein response … read more

Project leader: Alessandra Polissi
Envelope biogenesis in Gram-negative bacteria as molecular target for the development of next generation antibacterial drugs … read more

Project leader: Laura Popolo
Exploiting the CRISPR-Cas9 technology to study the double strand DNA break repair and genome stability … read more

Project leader: Stefano Ricagno
Dissecting the molecular bases of Human Light Chains “soluble toxicity” … read more

Project leader: Thomas Vaccari
USP36, a novel repressor of Notch signaling in human cells … read more

Project leader: Federico Zambelli
Development and implementation of cloud-oriented bioinformatic tools and workflows … read more

Project leader: Lucia Colombo
New insights in germ line development in plants … read more

Project leader: Graziella Cappelletti
Modulatin of lysosome function and α-sinuclein accumulation by Leucine-Rich Repeat Kinase 2 (LRRK2): towards a pathway for Parkinson’s disease … read more



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